Machine Learning-based Classifiers for the Prediction of Low Birth Weight

Objectives Low birth weight (LBW) is a global concern associated with fetal and neonatal mortality as well as adverse consequences such as intellectual disability, impaired cognitive development, and chronic diseases in adulthood. Numerous factors contribute to LBW and vary based on the region. The...

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Main Authors: Mahya Arayeshgari, Somayeh Najafi-Ghobadi, Hosein Tarhsaz, Sharareh Parami, Leili Tapak
Format: Article
Language:English
Published: The Korean Society of Medical Informatics 2023-01-01
Series:Healthcare Informatics Research
Subjects:
Online Access:http://www.e-hir.org/upload/pdf/hir-2023-29-1-54.pdf
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author Mahya Arayeshgari
Somayeh Najafi-Ghobadi
Hosein Tarhsaz
Sharareh Parami
Leili Tapak
author_facet Mahya Arayeshgari
Somayeh Najafi-Ghobadi
Hosein Tarhsaz
Sharareh Parami
Leili Tapak
author_sort Mahya Arayeshgari
collection DOAJ
description Objectives Low birth weight (LBW) is a global concern associated with fetal and neonatal mortality as well as adverse consequences such as intellectual disability, impaired cognitive development, and chronic diseases in adulthood. Numerous factors contribute to LBW and vary based on the region. The main objectives of this study were to compare four machine learning classifiers in the prediction of LBW and to determine the most important factors related to this phenomenon in Hamadan, Iran. Methods We carried out a retrospective cross-sectional study on a dataset collected from Fatemieh Hospital in 2017 that included 741 mother-newborn pairs and 13 potential factors. Decision tree, random forest, artificial neural network, support vector machine, and logistic regression (LR) methods were used to predict LBW, with five evaluation criteria utilized to compare performance. Results Our findings revealed a 7% prevalence of LBW. The average accuracy of all models was 87% or higher. The LR method provided a sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and accuracy of 74%, 89%, 7.04%, 29%, and 88%, respectively. Using LR, gestational age, number of abortions, gravida, consanguinity, maternal age at delivery, and neonatal sex were determined to be the six most important variables associated with LBW. Conclusions Our findings underscore the importance of facilitating timely diagnosis of causes of abortion, providing genetic counseling to consanguineous couples, and strengthening care before and during pregnancy (particularly for young mothers) to reduce LBW.
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spelling doaj.art-6ab8d2f2727341ff98ab64d1ad4955912023-02-16T01:30:29ZengThe Korean Society of Medical InformaticsHealthcare Informatics Research2093-36812093-369X2023-01-01291546310.4258/hir.2023.29.1.541148Machine Learning-based Classifiers for the Prediction of Low Birth WeightMahya Arayeshgari0Somayeh Najafi-Ghobadi1Hosein Tarhsaz2Sharareh Parami3Leili Tapak4 Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran Department of Industrial Engineering, Faculty of Engineering, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IranObjectives Low birth weight (LBW) is a global concern associated with fetal and neonatal mortality as well as adverse consequences such as intellectual disability, impaired cognitive development, and chronic diseases in adulthood. Numerous factors contribute to LBW and vary based on the region. The main objectives of this study were to compare four machine learning classifiers in the prediction of LBW and to determine the most important factors related to this phenomenon in Hamadan, Iran. Methods We carried out a retrospective cross-sectional study on a dataset collected from Fatemieh Hospital in 2017 that included 741 mother-newborn pairs and 13 potential factors. Decision tree, random forest, artificial neural network, support vector machine, and logistic regression (LR) methods were used to predict LBW, with five evaluation criteria utilized to compare performance. Results Our findings revealed a 7% prevalence of LBW. The average accuracy of all models was 87% or higher. The LR method provided a sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and accuracy of 74%, 89%, 7.04%, 29%, and 88%, respectively. Using LR, gestational age, number of abortions, gravida, consanguinity, maternal age at delivery, and neonatal sex were determined to be the six most important variables associated with LBW. Conclusions Our findings underscore the importance of facilitating timely diagnosis of causes of abortion, providing genetic counseling to consanguineous couples, and strengthening care before and during pregnancy (particularly for young mothers) to reduce LBW.http://www.e-hir.org/upload/pdf/hir-2023-29-1-54.pdfinfantlow birth weightgestational ageabortioninducedlogistic modelsmachine learning
spellingShingle Mahya Arayeshgari
Somayeh Najafi-Ghobadi
Hosein Tarhsaz
Sharareh Parami
Leili Tapak
Machine Learning-based Classifiers for the Prediction of Low Birth Weight
Healthcare Informatics Research
infant
low birth weight
gestational age
abortion
induced
logistic models
machine learning
title Machine Learning-based Classifiers for the Prediction of Low Birth Weight
title_full Machine Learning-based Classifiers for the Prediction of Low Birth Weight
title_fullStr Machine Learning-based Classifiers for the Prediction of Low Birth Weight
title_full_unstemmed Machine Learning-based Classifiers for the Prediction of Low Birth Weight
title_short Machine Learning-based Classifiers for the Prediction of Low Birth Weight
title_sort machine learning based classifiers for the prediction of low birth weight
topic infant
low birth weight
gestational age
abortion
induced
logistic models
machine learning
url http://www.e-hir.org/upload/pdf/hir-2023-29-1-54.pdf
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