Accurate numerical integration of highly stiff pharmacokinetics models using continuous block implicit hybrid one-step collocation methods
The differential equations of pharmacokinetic models, obtained from the formulation based on the Fick's perfusion principle and law of conservation of mass action, deals with absorption, distribution, and elimination of drugs by the body systems. In the formulation, the ordinary differential eq...
Main Authors: | Gulibur Dauda Yakubu, Mohammed Abdulhameed, Garba Tahiru Adamu, Saidu Abubakar Kadas, Suleiman Aminu Tukur |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2023-03-01
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Series: | Journal of Algorithms & Computational Technology |
Online Access: | https://doi.org/10.1177/17483026231157197 |
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