Signal Transduction at the Domain Interface of Prokaryotic Pentameric Ligand-Gated Ion Channels.

Pentameric ligand-gated ion channels are activated by the binding of agonists to a site distant from the ion conduction path. These membrane proteins consist of distinct ligand-binding and pore domains that interact via an extended interface. Here, we have investigated the role of residues at this i...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Carlo Bertozzi, Iwan Zimmermann, Sibylle Engeler, Ricarda J C Hilf, Raimund Dutzler
التنسيق: مقال
اللغة:English
منشور في: Public Library of Science (PLoS) 2016-03-01
سلاسل:PLoS Biology
الوصول للمادة أونلاين:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1002393&type=printable