Agmatine inhibits nuclear factor-κB nuclear translocation in acute spinal cord compression injury rat model

Agmatine inhibits nuclear factor-κB nuclear translocation in acute spinal cord compression injury rat model

Secondary damage after acute spinal cord compression injury (SCCI) exacerbates initial insult. Nuclear factor kappa-B (NF-κB)-p65 activation is involved in SCCI deleterious effects. Agmatine (Agm) showed neuroprotection against various CNS injuries. However, Agm impact on NF-κB signaling in acute SC...

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Bibliographic Details
Main Authors: Doaa M. Samy, Passainte S. Hassan, Cherine A. Ismail, Mona A. Hady, Mohamed A. Eshra
Format: Article
Language:English
Published: Taylor & Francis Group 2016-09-01
Series:Alexandria Journal of Medicine
Subjects:
Spinal cord injury
Agmatine
Nuclear factor kappa B
Oxidative stress
Inflammation
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2090506815000706

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