Isoalantolactone protects against ethanol-induced gastric ulcer via alleviating inflammation through regulation of PI3K-Akt signaling pathway and Th17 cell differentiation

Isoalantolactone protects against ethanol-induced gastric ulcer via alleviating inflammation through regulation of PI3K-Akt signaling pathway and Th17 cell differentiation

Gastric ulcer (GU) is one of the most prevalent digestive system diseases in humans, and it has been linked to inflammation. Previous studies have demonstrated the anti-inflammatory potential of isoalantolactone (IAL), a sesquiterpene lactone isolated from Radix Inulae. However, the pharmacological...

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Bibliographic Details
Main Authors:	Chaoyi Zhou, Jing Chen, Kechun Liu, Kannan Maharajan, Yun Zhang, Linhua Hou, Jianheng Li, Ma Mi, Qing Xia
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Series:	Biomedicine & Pharmacotherapy
Subjects:	Isoalantolactone Gastric ulcer Anti-inflammatory effect Network pharmacology Zebrafish
Online Access:	http://www.sciencedirect.com/science/article/pii/S0753332223001038

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