MICU1 controls cristae junction and spatially anchors mitochondrial Ca2+ uniporter complex
Proper mitochondrial structure is critical for normal function. Here, the authors show with SIM that the mitochondrial Ca2+ uniporter complex and localization of component MICU1 is critical to maintaining cristae junction stability and overall mitochondrial membrane structure.
Bibliographic Details
Main Authors: |
Benjamin Gottschalk,
Christiane Klec,
Gerd Leitinger,
Eva Bernhart,
René Rost,
Helmut Bischof,
Corina T. Madreiter-Sokolowski,
Snježana Radulović,
Emrah Eroglu,
Wolfgang Sattler,
Markus Waldeck-Weiermair,
Roland Malli,
Wolfgang F. Graier |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2019-08-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-019-11692-x
|