Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis
Abstract Background Organisms living at high altitudes face low oxygen and temperature conditions; thus, the genetic mechanisms underlying the adaptations in these organisms merit investigation. The glyptosternoid fish, Creteuchiloglanis macropterus mainly inhabits regions with gradual increases in...
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BMC
2017-11-01
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| Series: | BMC Evolutionary Biology |
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| Online Access: | http://link.springer.com/article/10.1186/s12862-017-1074-0 |
| _version_ | 1818694049915207680 |
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| author | Jingliang Kang Xiuhui Ma Shunping He |
| author_facet | Jingliang Kang Xiuhui Ma Shunping He |
| author_sort | Jingliang Kang |
| collection | DOAJ |
| description | Abstract Background Organisms living at high altitudes face low oxygen and temperature conditions; thus, the genetic mechanisms underlying the adaptations in these organisms merit investigation. The glyptosternoid fish, Creteuchiloglanis macropterus mainly inhabits regions with gradual increases in altitudes along the Nujiang River and might serve as an appropriate evolutionary model for detecting adaptation processes in environments with altitude changes. Results We constructed eleven RNA-sequencing (RNA-seq) libraries of C. macropterus collected from five locations at different altitudes to identify the genetic signatures of high-altitude adaptation. The comparative genomic analysis indicated that C. macropterus has an accelerated evolutionary rate compared with that of fishes in the lowland, and fishes at higher altitudes might evolve faster. Functional enrichment analysis of the fast-evolving and positively selected genes, differentially expressed genes and highly expressed genes, showed that these genes were involved in many functions related to energy metabolism and hypoxia. Conclusions Our study provides evidence of high-altitude adaptation in C. macropterus, and the detected adaptive genes might be a resource for future investigations of adaptations to high-altitude environments in other fishes. |
| first_indexed | 2024-12-17T13:23:24Z |
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| id | doaj.art-6acddf4f249541d1b3ab539cd1d5273c |
| institution | Directory Open Access Journal |
| issn | 1471-2148 |
| language | English |
| last_indexed | 2024-12-17T13:23:24Z |
| publishDate | 2017-11-01 |
| publisher | BMC |
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| series | BMC Evolutionary Biology |
| spelling | doaj.art-6acddf4f249541d1b3ab539cd1d5273c2022-12-21T21:46:49ZengBMCBMC Evolutionary Biology1471-21482017-11-0117111210.1186/s12862-017-1074-0Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysisJingliang Kang0Xiuhui Ma1Shunping He2The Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of SciencesCollege of Animal Science, Guizhou UniversityThe Key Laboratory of Aquatic Biodiversity and Conservation of Chinese Academy of Sciences, Institute of Hydrobiology, Chinese Academy of SciencesAbstract Background Organisms living at high altitudes face low oxygen and temperature conditions; thus, the genetic mechanisms underlying the adaptations in these organisms merit investigation. The glyptosternoid fish, Creteuchiloglanis macropterus mainly inhabits regions with gradual increases in altitudes along the Nujiang River and might serve as an appropriate evolutionary model for detecting adaptation processes in environments with altitude changes. Results We constructed eleven RNA-sequencing (RNA-seq) libraries of C. macropterus collected from five locations at different altitudes to identify the genetic signatures of high-altitude adaptation. The comparative genomic analysis indicated that C. macropterus has an accelerated evolutionary rate compared with that of fishes in the lowland, and fishes at higher altitudes might evolve faster. Functional enrichment analysis of the fast-evolving and positively selected genes, differentially expressed genes and highly expressed genes, showed that these genes were involved in many functions related to energy metabolism and hypoxia. Conclusions Our study provides evidence of high-altitude adaptation in C. macropterus, and the detected adaptive genes might be a resource for future investigations of adaptations to high-altitude environments in other fishes.http://link.springer.com/article/10.1186/s12862-017-1074-0Creteuchiloglanis macropterusThe Nujiang RiverTranscriptomeHigh-altitude adaptationGene expression |
| spellingShingle | Jingliang Kang Xiuhui Ma Shunping He Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis BMC Evolutionary Biology Creteuchiloglanis macropterus The Nujiang River Transcriptome High-altitude adaptation Gene expression |
| title | Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis |
| title_full | Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis |
| title_fullStr | Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis |
| title_full_unstemmed | Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis |
| title_short | Evidence of high-altitude adaptation in the glyptosternoid fish, Creteuchiloglanis macropterus from the Nujiang River obtained through transcriptome analysis |
| title_sort | evidence of high altitude adaptation in the glyptosternoid fish creteuchiloglanis macropterus from the nujiang river obtained through transcriptome analysis |
| topic | Creteuchiloglanis macropterus The Nujiang River Transcriptome High-altitude adaptation Gene expression |
| url | http://link.springer.com/article/10.1186/s12862-017-1074-0 |
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