Delayed microglial activation associated with the resolution of neuroinflammation in a mouse model of sublethal endotoxemia-induced systemic inflammation

Delayed microglial activation associated with the resolution of neuroinflammation in a mouse model of sublethal endotoxemia-induced systemic inflammation

Systemic inflammation affects brain functions. In our previous study in which lipopolysaccharide (LPS) was injected intraperitoneally into mice at sublethal doses, choroid plexus macrophages produced interleukin-1β and stimulated neighboring stromal cells. Activated stromal cells stimulate choroid p...

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Bibliographic Details
Main Authors: Atsuyoshi Shimada, Makiko Murata, Sayaka Aoyagi, Hinami Asano, Aki Obara, Sanae Hasegawa-Ishii
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Toxicology Reports
Subjects:
Endotoxin
Systemic inflammation
Encephalopathy
Cytokine
Microglia
M2 phenotype
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750022001512

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