Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib

Recent advances in understanding spleen tyrosine kinase (SYK) in human biology and disease, with a focus on fostamatinib

Spleen tyrosine kinase (SYK) is an important regulatory molecule of signal transduction pathways involved in the pathogenesis of autoimmune diseases such as immune thrombocytopenia (ITP), and the SYK-signaling pathway has emerged as a potential target for the treatment of numerous diseases. The aim...

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Bibliographic Details
Main Authors: Nichola Cooper, Waleed Ghanima, Quentin A Hill, Phillip LR Nicolson, Vadim Markovtsov, Craig Kessler
Format: Article
Language:English
Published: Taylor & Francis Group 2023-01-01
Series:Platelets
Subjects:
cevidoplenib
entospletinib
fostamatinib
hmpl-523
spleen tyrosine kinase
syk
Online Access:http://dx.doi.org/10.1080/09537104.2022.2131751

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