The evolution and variety of RFamide-type neuropeptides: insights from deuterostomian invertebrates

The evolution and variety of RFamide-type neuropeptides: insights from deuterostomian invertebrates

Five families of neuropeptides that have a C-terminal RFamide motif have been identified in vertebrates: 1. gonadotropin-inhibitory hormone (GnIH), 2. neuropeptide FF (NPFF) 3. pyroglutamylated RFamide peptide (QRFP), 4. prolactin-releasing peptide (PrRP) and 5. Kisspeptin. Experimental demonstrati...

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Bibliographic Details
Main Authors: Maurice Richard Elphick, Olivier eMirabeau
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Endocrinology
Subjects:
evolution
receptor
Neuropeptide
RFamide
echinoderm
deuterostome
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00093/full

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