Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss

Targeted Deletion of Loxl3 by Col2a1-Cre Leads to Progressive Hearing Loss

Collagens are major constituents of the extracellular matrix (ECM) that play an essential role in the structure of the inner ear and provide elasticity and rigidity when the signals of sound are received and transformed into electrical signals. LOXL3 is a member of the lysyl oxidase (LOX) family tha...

Full description

Bibliographic Details
Main Authors: Ziyi Liu, Xinfeng Bai, Peifeng Wan, Fan Mo, Ge Chen, Jian Zhang, Jiangang Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Loxl3
hearing loss
spiral ligament
extracellular matrix
mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.683495/full

Similar Items

Similar Items