Cancer apelin receptor suppresses vascular mimicry in malignant melanoma

Cancer apelin receptor suppresses vascular mimicry in malignant melanoma

Several reports indicate that apelin is often over-expressed in tumors, and therefore it has been suggested that the apelin–apelin receptor (APJ) system may induce tumor progression. In contrast, our previous research revealed high expression of the apelin–APJ system in tumor blood vessels, suggesti...

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Bibliographic Details
Main Authors: Koichi Inukai, Kazuyoshi Kise, Yumiko Hayashi, Weizhen Jia, Fumitaka Muramatsu, Naoki Okamoto, Hirotaka Konishi, Keigo Akuta, Hiroyasu Kidoya, Nobuyuki Takakura
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Pathology and Oncology Research
Subjects:
epithelial-mesenchymal transition
melanoma
apelin
apelin receptor
neovascularization
Online Access:https://www.por-journal.com/articles/10.3389/pore.2023.1610867/full

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