Evaluation of the Potency of Two Pyolysin-Derived Recombinant Proteins as Vaccine Candidates of <i>Trueperella Pyogenes</i> in a Mouse Model: Pyolysin Oligomerization and Structural Change Affect the Efficacy of Pyolysin-Based Vaccines

Evaluation of the Potency of Two Pyolysin-Derived Recombinant Proteins as Vaccine Candidates of <i>Trueperella Pyogenes</i> in a Mouse Model: Pyolysin Oligomerization and Structural Change Affect the Efficacy of Pyolysin-Based Vaccines

<i>Trueperella pyogenes </i>(<i>T. pyogenes</i>)<i> </i>is an important opportunistic pathogen in livestock and wild animals. However, only one commercial<i> T. pyogenes </i>vaccine is currently available, and its immunoprotective effect is not ideal....

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Bibliographic Details
Main Authors: Lingxiao Yang, Hongmin Liang, Bing Wang, Bo Ma, Junwei Wang, Wenlong Zhang
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Vaccines
Subjects:
<i>trueperella pyogenes</i>
pyolysin
recombinant antigens
vaccine efficacy
oligomerization and structural changes
Online Access:https://www.mdpi.com/2076-393X/8/1/79

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