The Effect of Early Maternal Separation Combined With Adolescent Chronic Unpredictable Mild Stress on Behavior and Synaptic Plasticity in Adult Female Rats

The Effect of Early Maternal Separation Combined With Adolescent Chronic Unpredictable Mild Stress on Behavior and Synaptic Plasticity in Adult Female Rats

Our aims were to evaluate the depression model of early maternal separation (MS) combined with adolescent chronic unpredictable mild stress (CUMS) in female adult SD rats to observe the behavior and the expressions of synaptic proteins in rats and to provide a reference for the screening of antidepr...

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Bibliographic Details
Main Authors: Jiawen Huang, Chongkun Shen, Ran Ye, Yafei Shi, Weirong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Psychiatry
Subjects:
maternal separation
depression
anxiety
synaptic plasticity
early stress
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2021.539299/full

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