Safety and efficacy of a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp. CNCM I‐3699 for chickens for fattening (STI Biotechnologie)
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Sorbiflore® ADVANCE, a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐369...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-03-01
|
| Series: | EFSA Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.2903/j.efsa.2023.7857 |
| _version_ | 1797829757931356160 |
|---|---|
| author | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen Birgit Dusemund Mojca Durjava Maryline Kouba Marta López‐Alonso Secundino López Puente Francesca Marcon Baltasar Mayo Alena Pechová Mariana Petkova Fernando Ramos Yolanda Sanz Roberto Edoardo Villa Ruud Woutersen Pier Sandro Cocconcelli Elisa Pettenati Montserrat Anguita Rosella Brozzi |
| author_facet | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen Birgit Dusemund Mojca Durjava Maryline Kouba Marta López‐Alonso Secundino López Puente Francesca Marcon Baltasar Mayo Alena Pechová Mariana Petkova Fernando Ramos Yolanda Sanz Roberto Edoardo Villa Ruud Woutersen Pier Sandro Cocconcelli Elisa Pettenati Montserrat Anguita Rosella Brozzi |
| author_sort | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) |
| collection | DOAJ |
| description | Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Sorbiflore® ADVANCE, a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp.CNCM I‐3699 intended to be used as a zootechnical additive (functional group: other zootechnical additives) in feed for chickens for fattening to improve their performance. In a previous opinion, the additive was described as containing viable but not cultivable cells of the two strains in a 1:1 ratio, with a minimum of total lactic acid bacteria counts of 5 × 108 viable forming units (VFU)/g additive. However, in that opinion, the Panel could not fully characterise the additive or conclude on its dermal/ocular irritancy or sensitisation potential. In the current assessment, the applicant provided supplementary information to address the missing information for the characterisation of the additive. The proposed methodology to discriminate and individually quantify the two strains composing the additive still presented limitations. Therefore, the Panel concluded that the data available do not allow to fully characterise the additive. The Panel was not in the position to conclude on the taxonomical identification of the strain CNCM I‐3699, and consequently, on its eligibility for the application of the qualified presumption of safety (QPS) approach. Therefore, the previous conclusions on the safety of the additive based on the QPS approach could not be confirmed. The Panel was not in the position to conclude on the safety of the additive for the target species, consumer and the environment. Sorbiflore® ADVANCE is not irritant to skin. The Panel could not conclude on the eye irritancy or skin sensitisation potential of the additive. |
| first_indexed | 2024-04-09T13:25:18Z |
| format | Article |
| id | doaj.art-6af65348ce6b434099046dda2be31f10 |
| institution | Directory Open Access Journal |
| issn | 1831-4732 |
| language | English |
| last_indexed | 2024-04-09T13:25:18Z |
| publishDate | 2023-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | EFSA Journal |
| spelling | doaj.art-6af65348ce6b434099046dda2be31f102023-05-10T11:11:19ZengWileyEFSA Journal1831-47322023-03-01213n/an/a10.2903/j.efsa.2023.7857Safety and efficacy of a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp. CNCM I‐3699 for chickens for fattening (STI Biotechnologie)EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)Vasileios BampidisGiovanna AzimontiMaria de Lourdes BastosHenrik ChristensenBirgit DusemundMojca DurjavaMaryline KoubaMarta López‐AlonsoSecundino López PuenteFrancesca MarconBaltasar MayoAlena PechováMariana PetkovaFernando RamosYolanda SanzRoberto Edoardo VillaRuud WoutersenPier Sandro CocconcelliElisa PettenatiMontserrat AnguitaRosella BrozziAbstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of Sorbiflore® ADVANCE, a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp.CNCM I‐3699 intended to be used as a zootechnical additive (functional group: other zootechnical additives) in feed for chickens for fattening to improve their performance. In a previous opinion, the additive was described as containing viable but not cultivable cells of the two strains in a 1:1 ratio, with a minimum of total lactic acid bacteria counts of 5 × 108 viable forming units (VFU)/g additive. However, in that opinion, the Panel could not fully characterise the additive or conclude on its dermal/ocular irritancy or sensitisation potential. In the current assessment, the applicant provided supplementary information to address the missing information for the characterisation of the additive. The proposed methodology to discriminate and individually quantify the two strains composing the additive still presented limitations. Therefore, the Panel concluded that the data available do not allow to fully characterise the additive. The Panel was not in the position to conclude on the taxonomical identification of the strain CNCM I‐3699, and consequently, on its eligibility for the application of the qualified presumption of safety (QPS) approach. Therefore, the previous conclusions on the safety of the additive based on the QPS approach could not be confirmed. The Panel was not in the position to conclude on the safety of the additive for the target species, consumer and the environment. Sorbiflore® ADVANCE is not irritant to skin. The Panel could not conclude on the eye irritancy or skin sensitisation potential of the additive.https://doi.org/10.2903/j.efsa.2023.7857zootechnical additivesother zootechnical additivesLacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp.CNCM I‐3699chickenssafety |
| spellingShingle | EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) Vasileios Bampidis Giovanna Azimonti Maria de Lourdes Bastos Henrik Christensen Birgit Dusemund Mojca Durjava Maryline Kouba Marta López‐Alonso Secundino López Puente Francesca Marcon Baltasar Mayo Alena Pechová Mariana Petkova Fernando Ramos Yolanda Sanz Roberto Edoardo Villa Ruud Woutersen Pier Sandro Cocconcelli Elisa Pettenati Montserrat Anguita Rosella Brozzi Safety and efficacy of a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp. CNCM I‐3699 for chickens for fattening (STI Biotechnologie) EFSA Journal zootechnical additives other zootechnical additives Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp.CNCM I‐3699 chickens safety |
| title | Safety and efficacy of a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp. CNCM I‐3699 for chickens for fattening (STI Biotechnologie) |
| title_full | Safety and efficacy of a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp. CNCM I‐3699 for chickens for fattening (STI Biotechnologie) |
| title_fullStr | Safety and efficacy of a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp. CNCM I‐3699 for chickens for fattening (STI Biotechnologie) |
| title_full_unstemmed | Safety and efficacy of a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp. CNCM I‐3699 for chickens for fattening (STI Biotechnologie) |
| title_short | Safety and efficacy of a feed additive consisting of Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp. CNCM I‐3699 for chickens for fattening (STI Biotechnologie) |
| title_sort | safety and efficacy of a feed additive consisting of lacticaseibacillus rhamnosus cncm i 3698 and companilactobacillus sp cncm i 3699 for chickens for fattening sti biotechnologie |
| topic | zootechnical additives other zootechnical additives Lacticaseibacillus rhamnosus CNCM I‐3698 and Companilactobacillus sp.CNCM I‐3699 chickens safety |
| url | https://doi.org/10.2903/j.efsa.2023.7857 |
| work_keys_str_mv | AT efsapanelonadditivesandproductsorsubstancesusedinanimalfeedfeedap safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT vasileiosbampidis safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT giovannaazimonti safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT mariadelourdesbastos safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT henrikchristensen safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT birgitdusemund safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT mojcadurjava safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT marylinekouba safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT martalopezalonso safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT secundinolopezpuente safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT francescamarcon safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT baltasarmayo safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT alenapechova safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT marianapetkova safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT fernandoramos safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT yolandasanz safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT robertoedoardovilla safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT ruudwoutersen safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT piersandrococconcelli safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT elisapettenati safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT montserratanguita safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie AT rosellabrozzi safetyandefficacyofafeedadditiveconsistingoflacticaseibacillusrhamnosuscncmi3698andcompanilactobacillusspcncmi3699forchickensforfatteningstibiotechnologie |