BF<sub>3</sub>-OEt<sub>2</sub> Catalyzed C3-Alkylation of Indole: Synthesis of Indolylsuccinimidesand Their Cytotoxicity Studies

BF<sub>3</sub>-OEt<sub>2</sub> Catalyzed C3-Alkylation of Indole: Synthesis of Indolylsuccinimidesand Their Cytotoxicity Studies

A simple and efficient BF<sub>3</sub>-OEt<sub>2</sub> promoted C3-alkylation of indole has been developed to obtain3-indolylsuccinimidesfrom commercially available indoles and maleimides, with excellent yields under mild reaction conditions. Furthermore, anti-proliferative ac...

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Bibliographic Details
Main Authors: Iqbal N. Shaikh, Abdul Rahim, Shaikh Faazil, Syed Farooq Adil, Mohamed E. Assal, Mohammad Rafe Hatshan
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
C3-alkylation
indole
indolylsuccinimides
cytotoxicity
anticancer
Online Access:https://www.mdpi.com/1420-3049/26/8/2202

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