Modified Iron Deposition in Nigrosomes by Pharmacotherapy for the Management of Parkinson’s Disease

Modified Iron Deposition in Nigrosomes by Pharmacotherapy for the Management of Parkinson’s Disease

Background: Increased iron deposition in nigrosome as assessed by susceptibility-weighted imaging (SWI) is involved in the pathogenesis of Parkinson’s disease (PD). This study investigated the effects of antiparkinson drugs on iron deposition in the nigrosome of PD patients.Methods: Based on the ret...

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Bibliographic Details
Main Authors: Mengdi Wang, Hongxia Wang, Jing Wang, Shujun Lu, Chen Li, Xiaofei Zhong, Nan Wang, Ruli Ge, Qi Zheng, Jinbo Chen, Hongcai Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Molecular Biosciences
Subjects:
iron accumulation
nigrosome
Parkinson’s disease
levodopa
dorsolateral nigral hyperintensity
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.908298/full

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