P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis

P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis

Abstract Microglia survey the brain microenvironment for signals of injury or infection and are essential for the initiation and resolution of pathogen‐ or tissue damage‐induced inflammation. Understanding the mechanism of microglia responses during pathology is hence vital to promote regenerative r...

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Bibliographic Details
Main Authors: Alazne Zabala, Nuria Vazquez‐Villoldo, Björn Rissiek, Jon Gejo, Abraham Martin, Aitor Palomino, Alberto Perez‐Samartín, Krishna R Pulagam, Marco Lukowiak, Estibaliz Capetillo‐Zarate, Jordi Llop, Tim Magnus, Friedrich Koch‐Nolte, Francois Rassendren, Carlos Matute, María Domercq
Format: Article
Language:English
Published: Springer Nature 2018-08-01
Series:EMBO Molecular Medicine
Subjects:
microglia
myelin phagocytosis
P2X4 receptor
remyelination
Online Access:https://doi.org/10.15252/emmm.201708743

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