Cryo-EM structure of VASH1-SVBP bound to microtubules

Cryo-EM structure of VASH1-SVBP bound to microtubules

The dynamic tyrosination-detyrosination cycle of α-tubulin regulates microtubule functions. Perturbation of this cycle impairs mitosis, neural physiology, and cardiomyocyte contraction. The carboxypeptidases vasohibins 1 and 2 (VASH1 and VASH2), in complex with the small vasohibin-binding protein (S...

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Bibliographic Details
Main Authors: Faxiang Li, Yang Li, Xuecheng Ye, Haishan Gao, Zhubing Shi, Xuelian Luo, Luke M Rice, Hongtao Yu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
microtubule
posttranslational modification
cryo-electron microscopy
detyrosination
vasohibin
Online Access:https://elifesciences.org/articles/58157

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