Three to Tango: Inhibitory Effect of Quercetin and Apigenin on Acetylcholinesterase, Amyloid-β Aggregation and Acetylcholinesterase-Amyloid Interaction

Three to Tango: Inhibitory Effect of Quercetin and Apigenin on Acetylcholinesterase, Amyloid-β Aggregation and Acetylcholinesterase-Amyloid Interaction

One of the pathological hallmarks of Alzheimer’s disease (AD) is the formation of amyloid-β plaques. Since acetylcholinesterase (AChE) promotes the formation of such plaques, the inhibition of this enzyme could slow down the progression of amyloid-β aggregation, hence being complementary to the pall...

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Bibliographic Details
Main Authors: Irene Álvarez-Berbel, Alba Espargaró, Antonio Viayna, Ana Belén Caballero, Maria Antònia Busquets, Patrick Gámez, Francisco Javier Luque, Raimon Sabaté
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Pharmaceutics
Subjects:
antiamyloid
anti-Alzheimer
apigenin
quercetin
hydroxyflavones
polyphenols
Online Access:https://www.mdpi.com/1999-4923/14/11/2342

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