Comparative analysis of anxiety/depression scores in COVID-19 patients with disease severity, sleep patterns, and certain laboratory test results
Introduction Coronavirus disease 2019 (COVID-19) is associated with severe emotional changes. This research aims to investigate the prevalence of anxiety and depression in COVID-19 patients and its relationship with disease severity, sleep patterns, lifestyle, and specific laboratory test results....
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Termedia Publishing House
2021-05-01
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| Series: | Archives of Medical Science |
| Subjects: | |
| Online Access: | https://www.archivesofmedicalscience.com/Comparative-analysis-of-anxiety-depression-scores-in-COVID-19-patients-with-disease,136111,0,2.html |
| _version_ | 1827620368088563712 |
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| author | Zi-Qiang Meng Qi Leng Xu Wang Chun-Hai Xu Jing Xu Yan Liu |
| author_facet | Zi-Qiang Meng Qi Leng Xu Wang Chun-Hai Xu Jing Xu Yan Liu |
| author_sort | Zi-Qiang Meng |
| collection | DOAJ |
| description | Introduction
Coronavirus disease 2019 (COVID-19) is associated with severe emotional changes. This research aims to investigate the prevalence of anxiety and depression in COVID-19 patients and its relationship with disease severity, sleep patterns, lifestyle, and specific laboratory test results.
Material and methods
An observational study of 52 Chinese patients with COVID-19 was conducted to assess the relation between anxiety and depression (evaluated with the Hospital Anxiety and Depression Scale) and laboratory findings (lymphocytes, C-reactive proteins, leukocytes, alanine aminotransferase, aspartate aminotransferase). The relationships between the severity of COVID-19 in patients, the Insomnia Severity Index (ISI) score, and the Hospital Anxiety and Depression Scale (HADS) score were also investigated.
Results
There were statistically significant associations between disease, smoking, and HADS-A scores (p = 0.011/0.020). The HADS-D score of patients with the disease was higher than in those without a past medical history (p = 0.008). The difference in C-reactive protein (CRP) between different lung infections, the HADS-A and HADS-D scores between different ages and ISI groups, and the correlation between the two scores were statistically significant.
Conclusions
Anxiety and depression are associated with poor sleep quality, smoking, and past medical history in patients with COVID-19. Additionally, anxiety and depression were seen to coexist, and there was a positive correlation between them. Further, the inflammatory index CRP was significantly increased in bilateral lung infections. |
| first_indexed | 2024-03-09T10:46:29Z |
| format | Article |
| id | doaj.art-6b0f500b7eb6423bb69c63773b22ffd4 |
| institution | Directory Open Access Journal |
| issn | 1734-1922 1896-9151 |
| language | English |
| last_indexed | 2024-03-09T10:46:29Z |
| publishDate | 2021-05-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj.art-6b0f500b7eb6423bb69c63773b22ffd42023-12-01T10:00:43ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512021-05-011851262127010.5114/aoms/136111136111Comparative analysis of anxiety/depression scores in COVID-19 patients with disease severity, sleep patterns, and certain laboratory test resultsZi-Qiang Meng0Qi Leng1Xu Wang2Chun-Hai Xu3Jing Xu4Yan Liu5Department of Hepatology, Xixi Hospital of Hangzhou, Hangzhou, ChinaDepartment of Geriatrics, The First Affiliated Hospital, College of Medicine, Zhejiang University, ChinaDepartment of Ophthalmology, Xixi Hospital of Hangzhou, ChinaDepartment of Infection, The Second Affiliated Hospital of Harbin Medical University, ChinaDepartment of Hepatology, Xixi Hospital of Hangzhou, Hangzhou, ChinaDepartment of Hepatology, Xixi Hospital of Hangzhou, Hangzhou, ChinaIntroduction Coronavirus disease 2019 (COVID-19) is associated with severe emotional changes. This research aims to investigate the prevalence of anxiety and depression in COVID-19 patients and its relationship with disease severity, sleep patterns, lifestyle, and specific laboratory test results. Material and methods An observational study of 52 Chinese patients with COVID-19 was conducted to assess the relation between anxiety and depression (evaluated with the Hospital Anxiety and Depression Scale) and laboratory findings (lymphocytes, C-reactive proteins, leukocytes, alanine aminotransferase, aspartate aminotransferase). The relationships between the severity of COVID-19 in patients, the Insomnia Severity Index (ISI) score, and the Hospital Anxiety and Depression Scale (HADS) score were also investigated. Results There were statistically significant associations between disease, smoking, and HADS-A scores (p = 0.011/0.020). The HADS-D score of patients with the disease was higher than in those without a past medical history (p = 0.008). The difference in C-reactive protein (CRP) between different lung infections, the HADS-A and HADS-D scores between different ages and ISI groups, and the correlation between the two scores were statistically significant. Conclusions Anxiety and depression are associated with poor sleep quality, smoking, and past medical history in patients with COVID-19. Additionally, anxiety and depression were seen to coexist, and there was a positive correlation between them. Further, the inflammatory index CRP was significantly increased in bilateral lung infections.https://www.archivesofmedicalscience.com/Comparative-analysis-of-anxiety-depression-scores-in-COVID-19-patients-with-disease,136111,0,2.htmlanxietydepressioncovid-19insomnia severity index (isi) scorehospital anxiety and depression scale (hads) score |
| spellingShingle | Zi-Qiang Meng Qi Leng Xu Wang Chun-Hai Xu Jing Xu Yan Liu Comparative analysis of anxiety/depression scores in COVID-19 patients with disease severity, sleep patterns, and certain laboratory test results Archives of Medical Science anxiety depression covid-19 insomnia severity index (isi) score hospital anxiety and depression scale (hads) score |
| title | Comparative analysis of anxiety/depression scores in COVID-19 patients with disease severity, sleep patterns, and certain laboratory test results |
| title_full | Comparative analysis of anxiety/depression scores in COVID-19 patients with disease severity, sleep patterns, and certain laboratory test results |
| title_fullStr | Comparative analysis of anxiety/depression scores in COVID-19 patients with disease severity, sleep patterns, and certain laboratory test results |
| title_full_unstemmed | Comparative analysis of anxiety/depression scores in COVID-19 patients with disease severity, sleep patterns, and certain laboratory test results |
| title_short | Comparative analysis of anxiety/depression scores in COVID-19 patients with disease severity, sleep patterns, and certain laboratory test results |
| title_sort | comparative analysis of anxiety depression scores in covid 19 patients with disease severity sleep patterns and certain laboratory test results |
| topic | anxiety depression covid-19 insomnia severity index (isi) score hospital anxiety and depression scale (hads) score |
| url | https://www.archivesofmedicalscience.com/Comparative-analysis-of-anxiety-depression-scores-in-COVID-19-patients-with-disease,136111,0,2.html |
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