Cigarette smoke extract combined with LPS reduces ABCA3 expression in chronic pulmonary inflammation may be related to PPARγ/ P38 MAPK signaling pathway

Cigarette smoke extract combined with LPS reduces ABCA3 expression in chronic pulmonary inflammation may be related to PPARγ/ P38 MAPK signaling pathway

ABCA3 (ATP-binding cassette class A3) is a transmembrane transporter that plays a positive role in chronic pulmonary inflammation by regulating lipid metabolism. However, it is not completely clear whether ABCA3 and its signaling factors are involved in chronic pulmonary inflammation induced by the...

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Bibliographic Details
Main Authors: Shuyi Zhang, Xianwang Lu, Xin Fang, Zihao Wang, Shihao Cheng, Jue Song
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Chronic pulmonary inflammation
Cigarette smoke extract
Lipid metabolism
ABCA3
P38 MAPK
PPARγ
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651322009265

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http://www.sciencedirect.com/science/article/pii/S0147651322009265

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