Vps54 regulates Drosophila neuromuscular junction development and interacts genetically with Rab7 to control composition of the postsynaptic density

Vps54 regulates Drosophila neuromuscular junction development and interacts genetically with Rab7 to control composition of the postsynaptic density

Vps54 is a subunit of the Golgi-associated retrograde protein (GARP) complex, which is involved in tethering endosome-derived vesicles to the trans-Golgi network (TGN). In the wobbler mouse, a model for human motor neuron (MN) disease, reduction in the levels of Vps54 causes neurodegeneration. Howev...

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Bibliographic Details
Main Authors: Prajal H. Patel, Emily C. Wilkinson, Emily L. Starke, Malea R. McGimsey, J. Todd Blankenship, Scott A. Barbee
Format: Article
Language:English
Published: The Company of Biologists 2020-08-01
Series:Biology Open
Subjects:
drosophila
garp
rab7
vps54
neurodevelopment
neuromuscular junction
Online Access:http://bio.biologists.org/content/9/8/bio053421

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