Effect of Ginger and Novafen on menstrual pain: A cross-over trial

Objective: Menstrual pain is a periodic pain which happens during the days of menses. The menstrual disturbances as a health problem among young girls affect not only reproductive, but also psychical health and quality of life. This study was done with the goal of comparing the effect of Ginger and...

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Main Authors: Hajar Adib Rad, Zahra Basirat, Fatemeh Bakouei, Ali Akbar Moghadamnia, Soraya Khafri, Zeynab Farhadi Kotenaei, Maryam Nikpour, Somayeh Kazemi
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455918302304
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author Hajar Adib Rad
Zahra Basirat
Fatemeh Bakouei
Ali Akbar Moghadamnia
Soraya Khafri
Zeynab Farhadi Kotenaei
Maryam Nikpour
Somayeh Kazemi
author_facet Hajar Adib Rad
Zahra Basirat
Fatemeh Bakouei
Ali Akbar Moghadamnia
Soraya Khafri
Zeynab Farhadi Kotenaei
Maryam Nikpour
Somayeh Kazemi
author_sort Hajar Adib Rad
collection DOAJ
description Objective: Menstrual pain is a periodic pain which happens during the days of menses. The menstrual disturbances as a health problem among young girls affect not only reproductive, but also psychical health and quality of life. This study was done with the goal of comparing the effect of Ginger and Novafen on the menstrual pain. Materials and methods: This crossover clinical trial study was done in Iran on 168 single girl students 18–26 years old in Babol University of Medical Sciences with primary menstrual pain. The participants were randomly allocated to two groups receiving the drugs Novafen and Ginger. At the beginning of pain, in the two groups 200 mg capsule was given every 6 h for two serial cycles. Pain severity was measured by the visual scale before treatment, 1 h after consuming the drug (for 24 h) and 48 h after the onset of drug. Results: The mean age of participants was 21.83 ± 2.07 years. It has been reported that the intensity of pain from dysmenorrhea decreased in the Novafen and Ginger groups. Before treatment, the average pain intensity in Novafen and Ginger users were 7.12 ± 2.32 and 7.60 ± 1.84, respectively and after treatment pain intensity decreased to 3.10 ± 2.69 and 2.97 ± 2.69, respectively. Differences between two groups each time showed no statistical significance (p > 0.05). Conclusion: Both drugs reduced menstrual pain. Ginger as well as Novafen is effective in relieving pain in girls with primary dysmenorrhea . Therefore, treatment with natural herbal medicine, non-synthetic drug, to reduce primary dysmenorrhea is recommended. Keywords: Novafen, Ginger, Primary dysmenorrhea, Pain relieving
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spelling doaj.art-6b1a22e826704fbbbde452c1795f2d2c2022-12-22T02:26:57ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592018-12-01576806809Effect of Ginger and Novafen on menstrual pain: A cross-over trialHajar Adib Rad0Zahra Basirat1Fatemeh Bakouei2Ali Akbar Moghadamnia3Soraya Khafri4Zeynab Farhadi Kotenaei5Maryam Nikpour6Somayeh Kazemi7Infertility and Health Reproductive Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Islamic Republic of IranInfertility and Health Reproductive Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Islamic Republic of IranInfertility and Health Reproductive Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Islamic Republic of IranCellular and Molecular Biology Research Center, Health Research Institute, Department of Pharmacology, Babol University of Medical Sciences, Babol, Islamic Republic of IranInfertility and Health Reproductive Research Center, Health Research Institute, Department of Statistic and Epidemiology, Babol University of Medical Sciences, Babol, Islamic Republic of IranSocial Determinants of Health Research Center, Health Research Institute, Department of Nursing, Babol University of Medical Sciences, Babol, Islamic Republic of Iran; Corresponding author. Fax: +0098 11 32199936.Social Determinants of Health Research Center, Health Research Institute, Department of Midwifery, Babol University of Medical Sciences, Babol, Islamic Republic of IranDepartment of Midwifery, Babol University of Medical Sciences, Babol, Islamic Republic of IranObjective: Menstrual pain is a periodic pain which happens during the days of menses. The menstrual disturbances as a health problem among young girls affect not only reproductive, but also psychical health and quality of life. This study was done with the goal of comparing the effect of Ginger and Novafen on the menstrual pain. Materials and methods: This crossover clinical trial study was done in Iran on 168 single girl students 18–26 years old in Babol University of Medical Sciences with primary menstrual pain. The participants were randomly allocated to two groups receiving the drugs Novafen and Ginger. At the beginning of pain, in the two groups 200 mg capsule was given every 6 h for two serial cycles. Pain severity was measured by the visual scale before treatment, 1 h after consuming the drug (for 24 h) and 48 h after the onset of drug. Results: The mean age of participants was 21.83 ± 2.07 years. It has been reported that the intensity of pain from dysmenorrhea decreased in the Novafen and Ginger groups. Before treatment, the average pain intensity in Novafen and Ginger users were 7.12 ± 2.32 and 7.60 ± 1.84, respectively and after treatment pain intensity decreased to 3.10 ± 2.69 and 2.97 ± 2.69, respectively. Differences between two groups each time showed no statistical significance (p > 0.05). Conclusion: Both drugs reduced menstrual pain. Ginger as well as Novafen is effective in relieving pain in girls with primary dysmenorrhea . Therefore, treatment with natural herbal medicine, non-synthetic drug, to reduce primary dysmenorrhea is recommended. Keywords: Novafen, Ginger, Primary dysmenorrhea, Pain relievinghttp://www.sciencedirect.com/science/article/pii/S1028455918302304
spellingShingle Hajar Adib Rad
Zahra Basirat
Fatemeh Bakouei
Ali Akbar Moghadamnia
Soraya Khafri
Zeynab Farhadi Kotenaei
Maryam Nikpour
Somayeh Kazemi
Effect of Ginger and Novafen on menstrual pain: A cross-over trial
Taiwanese Journal of Obstetrics & Gynecology
title Effect of Ginger and Novafen on menstrual pain: A cross-over trial
title_full Effect of Ginger and Novafen on menstrual pain: A cross-over trial
title_fullStr Effect of Ginger and Novafen on menstrual pain: A cross-over trial
title_full_unstemmed Effect of Ginger and Novafen on menstrual pain: A cross-over trial
title_short Effect of Ginger and Novafen on menstrual pain: A cross-over trial
title_sort effect of ginger and novafen on menstrual pain a cross over trial
url http://www.sciencedirect.com/science/article/pii/S1028455918302304
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