Impact of off-hour admission on the MACEs of patients with acute myocardial infarction

Background In China, on more than 100 weekends or holidays, only on-duty cardiologists are available during admissions. This study aimed to analyze the impact of admission time on major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI). Methods This prospective...

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Main Authors: Qiuhong Jiang, Nan Zhang, Hongyu Zhang, Yongjian Xiao, Xia Zhang, Jing Gao, Yin Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2023.2186317
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author Qiuhong Jiang
Nan Zhang
Hongyu Zhang
Yongjian Xiao
Xia Zhang
Jing Gao
Yin Liu
author_facet Qiuhong Jiang
Nan Zhang
Hongyu Zhang
Yongjian Xiao
Xia Zhang
Jing Gao
Yin Liu
author_sort Qiuhong Jiang
collection DOAJ
description Background In China, on more than 100 weekends or holidays, only on-duty cardiologists are available during admissions. This study aimed to analyze the impact of admission time on major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI). Methods This prospective observational study enrolled patients with AMI between October 2018 and July 2019. The patients were assorted into off-hour (admitted on weekends or national holidays) and on-hour groups. The outcome was MACEs at admission and 1 year after discharge. Results A total of 485 patients with AMI were enrolled in this study. The occurrence of MACEs was significantly higher in the off-hour group compared with the on-hour group (P < .05). Multivariate regression analysis showed that age (HR = 1.047, 95% CI: 1.021–1.073), blood glucose level (HR = 1.029, 95% CI: 1.009–1.050), multivessel disease (HR = 1.904, 95% CI: 1.074–3.375), and off-hour hospital admission (HR = 1.849, 95% CI: 1.125–3.039) were all independent risk factors for in-hospital MACEs, while percutaneous coronary intervention (HR = 0.210, 95% CI: 0.147–0.300) and on-hour admission (HR = 0.723, 95% CI: 0.532–0.984) were protective factors for MACEs 1 year after discharge. Conclusion The “off-hour effect” still existed in patients with AMI, and the risk of MACEs in the hospital and 1 year after discharge was higher for off-hour admission.
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spelling doaj.art-6b1b4a9f6635498fabcb38050f99cf742023-09-19T16:04:08ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062023-12-0145110.1080/10641963.2023.21863172186317Impact of off-hour admission on the MACEs of patients with acute myocardial infarctionQiuhong Jiang0Nan Zhang1Hongyu Zhang2Yongjian Xiao3Xia Zhang4Jing Gao5Yin Liu6Baodi Clinical College of Tianjin Medical UniversityTianjin Chest HospitalBaodi Clinical College of Tianjin Medical UniversityTianjin Chest HospitalBaodi Clinical College of Tianjin Medical UniversityTianjin Chest HospitalTianjin Chest HospitalBackground In China, on more than 100 weekends or holidays, only on-duty cardiologists are available during admissions. This study aimed to analyze the impact of admission time on major adverse cardiovascular events (MACEs) in patients with acute myocardial infarction (AMI). Methods This prospective observational study enrolled patients with AMI between October 2018 and July 2019. The patients were assorted into off-hour (admitted on weekends or national holidays) and on-hour groups. The outcome was MACEs at admission and 1 year after discharge. Results A total of 485 patients with AMI were enrolled in this study. The occurrence of MACEs was significantly higher in the off-hour group compared with the on-hour group (P < .05). Multivariate regression analysis showed that age (HR = 1.047, 95% CI: 1.021–1.073), blood glucose level (HR = 1.029, 95% CI: 1.009–1.050), multivessel disease (HR = 1.904, 95% CI: 1.074–3.375), and off-hour hospital admission (HR = 1.849, 95% CI: 1.125–3.039) were all independent risk factors for in-hospital MACEs, while percutaneous coronary intervention (HR = 0.210, 95% CI: 0.147–0.300) and on-hour admission (HR = 0.723, 95% CI: 0.532–0.984) were protective factors for MACEs 1 year after discharge. Conclusion The “off-hour effect” still existed in patients with AMI, and the risk of MACEs in the hospital and 1 year after discharge was higher for off-hour admission.http://dx.doi.org/10.1080/10641963.2023.2186317chinamyocardial infarctionoff-hourpercutaneous coronary interventionrisk factor
spellingShingle Qiuhong Jiang
Nan Zhang
Hongyu Zhang
Yongjian Xiao
Xia Zhang
Jing Gao
Yin Liu
Impact of off-hour admission on the MACEs of patients with acute myocardial infarction
Clinical and Experimental Hypertension
china
myocardial infarction
off-hour
percutaneous coronary intervention
risk factor
title Impact of off-hour admission on the MACEs of patients with acute myocardial infarction
title_full Impact of off-hour admission on the MACEs of patients with acute myocardial infarction
title_fullStr Impact of off-hour admission on the MACEs of patients with acute myocardial infarction
title_full_unstemmed Impact of off-hour admission on the MACEs of patients with acute myocardial infarction
title_short Impact of off-hour admission on the MACEs of patients with acute myocardial infarction
title_sort impact of off hour admission on the maces of patients with acute myocardial infarction
topic china
myocardial infarction
off-hour
percutaneous coronary intervention
risk factor
url http://dx.doi.org/10.1080/10641963.2023.2186317
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