Correlation between Trace Element Levels in Iraqi Breast Cancer Patients
Breast Cancer (BC) is the most common disease in the human body in both sex , male and female ,Trace elements (TEs) like copper (Cu); zinc (Zn) and iron (Fe) have a vital role in biological and metabolic effects including activation or inhibition of enzymatic reaction, reactive oxygen spec...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
College of Pharmacy University of Baghdad
2023-09-01
|
| Series: | Iraqi Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/2055 |
| _version_ | 1797669505771503616 |
|---|---|
| author | Hadeel Alhashimy Shaymaa Abdulzahra Abbas |
| author_facet | Hadeel Alhashimy Shaymaa Abdulzahra Abbas |
| author_sort | Hadeel Alhashimy |
| collection | DOAJ |
| description |
Breast Cancer (BC) is the most common disease in the human body in both sex , male and female ,Trace elements (TEs) like copper (Cu); zinc (Zn) and iron (Fe) have a vital role in biological and metabolic effects including activation or inhibition of enzymatic reaction, reactive oxygen species (ROS), competition between trace elements and metal proteins for binding positions and modifications in the permeability of cellular membranes which affect on cancers events.This paper reviews measured trace elemental concentrations of cancerous and noncancerous blood sample by drawing 5 ml of venous blood from all patient and control (healthy persons) ,the serum was separated then used to measure the Zn,Cu and Fe. by using. a convenient colorimetric assay. The statistical significant association was determined, the p values is larger than 0.05 so the data considered statistically significant ,and there is a difference in the levels of trace elements (Zn, Cu and Fe) in four groups ; the median of Zn and Cu were highest in control group compared to the rest groups ,the median of Fe is highest in benign group compared to the rest groups .
|
| first_indexed | 2024-03-11T20:45:23Z |
| format | Article |
| id | doaj.art-6b1f7e6e531f48c09965b42b9f97e866 |
| institution | Directory Open Access Journal |
| issn | 2521-3512 1683-3597 |
| language | English |
| last_indexed | 2024-03-11T20:45:23Z |
| publishDate | 2023-09-01 |
| publisher | College of Pharmacy University of Baghdad |
| record_format | Article |
| series | Iraqi Journal of Pharmaceutical Sciences |
| spelling | doaj.art-6b1f7e6e531f48c09965b42b9f97e8662023-10-01T15:17:47ZengCollege of Pharmacy University of BaghdadIraqi Journal of Pharmaceutical Sciences2521-35121683-35972023-09-0132210.31351/vol32iss2pp58-64Correlation between Trace Element Levels in Iraqi Breast Cancer PatientsHadeel Alhashimy0Shaymaa Abdulzahra Abbas 1Wasit Health Department/ Ministry of Health and EnvironmentDepartment of Clinical Laboratory Sciences, College of Pharmacy, University of Baghdad, Baghdad, Iraq. Breast Cancer (BC) is the most common disease in the human body in both sex , male and female ,Trace elements (TEs) like copper (Cu); zinc (Zn) and iron (Fe) have a vital role in biological and metabolic effects including activation or inhibition of enzymatic reaction, reactive oxygen species (ROS), competition between trace elements and metal proteins for binding positions and modifications in the permeability of cellular membranes which affect on cancers events.This paper reviews measured trace elemental concentrations of cancerous and noncancerous blood sample by drawing 5 ml of venous blood from all patient and control (healthy persons) ,the serum was separated then used to measure the Zn,Cu and Fe. by using. a convenient colorimetric assay. The statistical significant association was determined, the p values is larger than 0.05 so the data considered statistically significant ,and there is a difference in the levels of trace elements (Zn, Cu and Fe) in four groups ; the median of Zn and Cu were highest in control group compared to the rest groups ,the median of Fe is highest in benign group compared to the rest groups . https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/2055Breast cancer, trace elements(TEs) ,colorimetric assay. oxidative stress (OxS), reactive oxygen species (ROS). |
| spellingShingle | Hadeel Alhashimy Shaymaa Abdulzahra Abbas Correlation between Trace Element Levels in Iraqi Breast Cancer Patients Iraqi Journal of Pharmaceutical Sciences Breast cancer, trace elements(TEs) ,colorimetric assay. oxidative stress (OxS), reactive oxygen species (ROS). |
| title | Correlation between Trace Element Levels in Iraqi Breast Cancer Patients |
| title_full | Correlation between Trace Element Levels in Iraqi Breast Cancer Patients |
| title_fullStr | Correlation between Trace Element Levels in Iraqi Breast Cancer Patients |
| title_full_unstemmed | Correlation between Trace Element Levels in Iraqi Breast Cancer Patients |
| title_short | Correlation between Trace Element Levels in Iraqi Breast Cancer Patients |
| title_sort | correlation between trace element levels in iraqi breast cancer patients |
| topic | Breast cancer, trace elements(TEs) ,colorimetric assay. oxidative stress (OxS), reactive oxygen species (ROS). |
| url | https://bijps.uobaghdad.edu.iq/index.php/bijps/article/view/2055 |
| work_keys_str_mv | AT hadeelalhashimy correlationbetweentraceelementlevelsiniraqibreastcancerpatients AT shaymaaabdulzahraabbas correlationbetweentraceelementlevelsiniraqibreastcancerpatients |