An African perspective on the prevalence, fate and effects of carbapenem resistance genes in hospital effluents and wastewater treatment plant (WWTP) final effluents: A critical review
This article provides an overview of the antibiotic era and discovery of earliest antibiotics until the present day state of affairs, coupled with the emergence of carbapenem-resistant bacteria. The ways of response to challenges of antibiotic resistance (AR) such as the development of novel strateg...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-05-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844020307441 |
| _version_ | 1811321476797693952 |
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| author | Kingsley Ehi Ebomah Anthony Ifeanyi Okoh |
| author_facet | Kingsley Ehi Ebomah Anthony Ifeanyi Okoh |
| author_sort | Kingsley Ehi Ebomah |
| collection | DOAJ |
| description | This article provides an overview of the antibiotic era and discovery of earliest antibiotics until the present day state of affairs, coupled with the emergence of carbapenem-resistant bacteria. The ways of response to challenges of antibiotic resistance (AR) such as the development of novel strategies in the search of new antibiotics, designing more effective preventive measures as well as the ecology of AR have been discussed. The applications of plant extract and chemical compounds like nanomaterials which are based on recent developments in the field of antimicrobials, antimicrobial resistance (AMR), and chemotherapy were briefly discussed. The agencies responsible for environmental protection have a role to play in dealing with the climate crisis which poses an existential threat to the planet, and contributes to ecological support towards pathogenic microorganisms. The environment serves as a reservoir and also a vehicle for transmission of antimicrobial resistance genes hence, as dominant inhabitants we have to gain a competitive advantage in the battle against AMR. |
| first_indexed | 2024-04-13T13:18:27Z |
| format | Article |
| id | doaj.art-6b1f8a8c388a49f191a74ece44023b09 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-13T13:18:27Z |
| publishDate | 2020-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-6b1f8a8c388a49f191a74ece44023b092022-12-22T02:45:24ZengElsevierHeliyon2405-84402020-05-0165e03899An African perspective on the prevalence, fate and effects of carbapenem resistance genes in hospital effluents and wastewater treatment plant (WWTP) final effluents: A critical reviewKingsley Ehi Ebomah0Anthony Ifeanyi Okoh1SAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice 5700, South Africa; Applied and Environmental Microbiology Research Group (AEMREG), Department of Biochemistry and Microbiology, University of Fort Hare, Alice 5700, South Africa; Corresponding author.SAMRC Microbial Water Quality Monitoring Centre, University of Fort Hare, Alice 5700, South Africa; Applied and Environmental Microbiology Research Group (AEMREG), Department of Biochemistry and Microbiology, University of Fort Hare, Alice 5700, South AfricaThis article provides an overview of the antibiotic era and discovery of earliest antibiotics until the present day state of affairs, coupled with the emergence of carbapenem-resistant bacteria. The ways of response to challenges of antibiotic resistance (AR) such as the development of novel strategies in the search of new antibiotics, designing more effective preventive measures as well as the ecology of AR have been discussed. The applications of plant extract and chemical compounds like nanomaterials which are based on recent developments in the field of antimicrobials, antimicrobial resistance (AMR), and chemotherapy were briefly discussed. The agencies responsible for environmental protection have a role to play in dealing with the climate crisis which poses an existential threat to the planet, and contributes to ecological support towards pathogenic microorganisms. The environment serves as a reservoir and also a vehicle for transmission of antimicrobial resistance genes hence, as dominant inhabitants we have to gain a competitive advantage in the battle against AMR.http://www.sciencedirect.com/science/article/pii/S2405844020307441BiotechnologyEnvironmental scienceMicrobiologyEpidemiologyEnvironmental healthEnvironmental pollution |
| spellingShingle | Kingsley Ehi Ebomah Anthony Ifeanyi Okoh An African perspective on the prevalence, fate and effects of carbapenem resistance genes in hospital effluents and wastewater treatment plant (WWTP) final effluents: A critical review Heliyon Biotechnology Environmental science Microbiology Epidemiology Environmental health Environmental pollution |
| title | An African perspective on the prevalence, fate and effects of carbapenem resistance genes in hospital effluents and wastewater treatment plant (WWTP) final effluents: A critical review |
| title_full | An African perspective on the prevalence, fate and effects of carbapenem resistance genes in hospital effluents and wastewater treatment plant (WWTP) final effluents: A critical review |
| title_fullStr | An African perspective on the prevalence, fate and effects of carbapenem resistance genes in hospital effluents and wastewater treatment plant (WWTP) final effluents: A critical review |
| title_full_unstemmed | An African perspective on the prevalence, fate and effects of carbapenem resistance genes in hospital effluents and wastewater treatment plant (WWTP) final effluents: A critical review |
| title_short | An African perspective on the prevalence, fate and effects of carbapenem resistance genes in hospital effluents and wastewater treatment plant (WWTP) final effluents: A critical review |
| title_sort | african perspective on the prevalence fate and effects of carbapenem resistance genes in hospital effluents and wastewater treatment plant wwtp final effluents a critical review |
| topic | Biotechnology Environmental science Microbiology Epidemiology Environmental health Environmental pollution |
| url | http://www.sciencedirect.com/science/article/pii/S2405844020307441 |
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