Association of the Synapse-Associated Protein 97 (SAP97) Gene Polymorphism With Neurocognitive Function in Schizophrenic Patients

Association of the Synapse-Associated Protein 97 (SAP97) Gene Polymorphism With Neurocognitive Function in Schizophrenic Patients

The SAP97 gene is located in the schizophrenia susceptibility locus 3q29, and it encodes the synaptic scaffolding protein that interacts with the N-methyl-D-aspartate (NMDA) receptor, which is presumed to be dysregulated in schizophrenia. In this study, we genotyped a single-nucleotide polymorphism...

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Bibliographic Details
Main Authors: Xusan Xu, Chunmei Liang, Dong Lv, Jingwen Yin, Xudong Luo, Jiawu Fu, Haifeng Yan, Xia Zhou, Zhun Dai, Dongjian Zhu, Susu Xiong, Zhixiong Lin, Juda Lin, Bin Zhao, You Li, Yajun Wang, Guoda Ma, Keshen Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Psychiatry
Subjects:
schizophrenia
synapse-associated protein 97 (SAP97) gene
L27 domain
rs3915512 polymorphism
neurocognitive function
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00458/full

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