Impact of preconditioning with retinoic acid during early development on morphological and functional characteristics of human induced pluripotent stem cell-derived neurons

Human induced pluripotent stem cells (hiPSCs) are a suitable tool to study basic molecular and cellular mechanisms of neurodevelopment. The directed differentiation of hiPSCs via the generation of a self-renewable neuronal precursor cell line allows the standardization of defined differentiation pro...

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Bibliographic Details
Main Authors: Sandra Horschitz, Friederike Matthäus, Anja Groß, Jan Rosner, Marta Galach, Wolfgang Greffrath, Rolf-Detlef Treede, Jochen Utikal, Patrick Schloss, Andreas Meyer-Lindenberg
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506115000495