Poloxamer 188 Attenuates Ischemia-Reperfusion-Induced Lung Injury by Maintaining Cell Membrane Integrity and Inhibiting Multiple Signaling Pathways

Poloxamer 188 Attenuates Ischemia-Reperfusion-Induced Lung Injury by Maintaining Cell Membrane Integrity and Inhibiting Multiple Signaling Pathways

Background: Poloxamer 188 (P188) possesses anti-inflammatory properties and can help to maintain plasma membrane function. P188 has been reported to exert beneficial effects in the treatment of various disorders. However, the effects of P188 in ischemia/reperfusion (IR)-induced acute lung injury hav...

Podrobná bibliografie
Hlavní autoři:	Shih-En Tang, Wen-I Liao, Hsin-Ping Pao, Chin-Wang Hsu, Shu-Yu Wu, Kun-Lun Huang, Shi-Jye Chu
Médium:	Článek
Jazyk:	English
Vydáno:	Frontiers Media S.A. 2021-07-01
Edice:	Frontiers in Pharmacology
Témata:	acute lung injury ischemia-reperfusion poloxamer 188 hypoxia/reoxygenation membrane integrity
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2021.650573/full

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