Rare Etiology of Odynophagia in a Female Adolescent

Herpes esophagitis (HE) is a rare condition in immunocompetent adolescents. However, it commonly occurs as a primary infection in younger individuals. Herein, we report a 16-year-old female patient who had a history of fever for 5 days, odynophagia, and orolabial herpes infection for 7 days. Cluster...

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Main Authors: Anastasios Koutsoumourakis, Asterios Gagalis, Maria Fotoulaki, Maria Stafylidou
Format: Article
Language:English
Published: Karger Publishers 2021-03-01
Series:Case Reports in Gastroenterology
Subjects:
Online Access:http://prod.karger.com/Article/FullText/513801
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author Anastasios Koutsoumourakis
Asterios Gagalis
Maria Fotoulaki
Maria Stafylidou
author_facet Anastasios Koutsoumourakis
Asterios Gagalis
Maria Fotoulaki
Maria Stafylidou
author_sort Anastasios Koutsoumourakis
collection DOAJ
description Herpes esophagitis (HE) is a rare condition in immunocompetent adolescents. However, it commonly occurs as a primary infection in younger individuals. Herein, we report a 16-year-old female patient who had a history of fever for 5 days, odynophagia, and orolabial herpes infection for 7 days. Clusters of painful vesicles on an erythematous base on the lips, gingiva, and palate were observed on physical examination. Further, esophagogastroduodenoscopy revealed diffuse linear ulcerations in the distal esophagus. The patient then received the following treatment: intravenous (I.V.) acyclovir 5 mg/kg three times a day, I.V. omeprazole 40 mg two times a day, and acyclovir 5% cream four times a day. After 8 days of admission, the patient was discharged. A follow-up esophagogastroduodenoscopy was performed 7 weeks after discharge, and the results revealed that the esophageal mucosa had a normal appearance. The effect of antiviral treatment against HE remains unknown in these patients. Nevertheless, it is believed to accelerate the healing process in individuals with esophageal mucosal barrier damage. To the best of our knowledge, this case of a female adolescent with an intact immune system is the sixth case of herpes simplex esophagitis to be reported in the literature.
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spelling doaj.art-6b2381a3043a4121b07490ac705c7daf2022-12-21T22:53:40ZengKarger PublishersCase Reports in Gastroenterology1662-06312021-03-0115135235810.1159/000513801513801Rare Etiology of Odynophagia in a Female AdolescentAnastasios Koutsoumourakis0Asterios Gagalis1Maria Fotoulaki2Maria Stafylidou3First Department of Internal Medicine, Papageorgiou Teaching Hospital, Thessaloniki, GreeceFirst Department of Internal Medicine, Papageorgiou Teaching Hospital, Thessaloniki, GreeceFourth Department of Pediatrics, Papageorgiou Teaching Hospital, Thessaloniki, GreeceFirst Department of Internal Medicine, Papageorgiou Teaching Hospital, Thessaloniki, GreeceHerpes esophagitis (HE) is a rare condition in immunocompetent adolescents. However, it commonly occurs as a primary infection in younger individuals. Herein, we report a 16-year-old female patient who had a history of fever for 5 days, odynophagia, and orolabial herpes infection for 7 days. Clusters of painful vesicles on an erythematous base on the lips, gingiva, and palate were observed on physical examination. Further, esophagogastroduodenoscopy revealed diffuse linear ulcerations in the distal esophagus. The patient then received the following treatment: intravenous (I.V.) acyclovir 5 mg/kg three times a day, I.V. omeprazole 40 mg two times a day, and acyclovir 5% cream four times a day. After 8 days of admission, the patient was discharged. A follow-up esophagogastroduodenoscopy was performed 7 weeks after discharge, and the results revealed that the esophageal mucosa had a normal appearance. The effect of antiviral treatment against HE remains unknown in these patients. Nevertheless, it is believed to accelerate the healing process in individuals with esophageal mucosal barrier damage. To the best of our knowledge, this case of a female adolescent with an intact immune system is the sixth case of herpes simplex esophagitis to be reported in the literature.http://prod.karger.com/Article/FullText/513801herpes esophagitisadolescentimmunocompetentacyclovir
spellingShingle Anastasios Koutsoumourakis
Asterios Gagalis
Maria Fotoulaki
Maria Stafylidou
Rare Etiology of Odynophagia in a Female Adolescent
Case Reports in Gastroenterology
herpes esophagitis
adolescent
immunocompetent
acyclovir
title Rare Etiology of Odynophagia in a Female Adolescent
title_full Rare Etiology of Odynophagia in a Female Adolescent
title_fullStr Rare Etiology of Odynophagia in a Female Adolescent
title_full_unstemmed Rare Etiology of Odynophagia in a Female Adolescent
title_short Rare Etiology of Odynophagia in a Female Adolescent
title_sort rare etiology of odynophagia in a female adolescent
topic herpes esophagitis
adolescent
immunocompetent
acyclovir
url http://prod.karger.com/Article/FullText/513801
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AT mariastafylidou rareetiologyofodynophagiainafemaleadolescent