Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments
Abstract Chemical biocides remain the most effective mitigation strategy against microbiologically influenced corrosion (MIC), one of the costliest and most pervasive forms of corrosion in industry. However, toxicity and environmental concerns associated with these compounds are encouraging the deve...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-94827-9 |
| _version_ | 1818696265903374336 |
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| author | Benjamin Tuck Elizabeth Watkin Maria Forsyth Anthony Somers Mahdi Ghorbani Laura L. Machuca |
| author_facet | Benjamin Tuck Elizabeth Watkin Maria Forsyth Anthony Somers Mahdi Ghorbani Laura L. Machuca |
| author_sort | Benjamin Tuck |
| collection | DOAJ |
| description | Abstract Chemical biocides remain the most effective mitigation strategy against microbiologically influenced corrosion (MIC), one of the costliest and most pervasive forms of corrosion in industry. However, toxicity and environmental concerns associated with these compounds are encouraging the development of more environmentally friendly MIC inhibitors. In this study, we evaluated the antimicrobial effect of a novel, multi-functional organic corrosion inhibitor (OCI) compound, cetrimonium trans-4-hydroxy-cinnamate (CTA-4OHcinn). Attachment of three bacterial strains, Shewanella chilikensis, Pseudomonas balearica and Klebsiella pneumoniae was evaluated on wet-ground (120 grit finish) and pre-oxidised carbon steel surfaces (AISI 1030), in the presence and absence of the new OCI compound. Our study revealed that all strains preferentially attached to pre-oxidised surfaces as indicated by confocal laser scanning microscopy, scanning electron microscopy and standard colony forming unit (CFU) quantification assays. The inhibitor compound at 10 mM demonstrated 100% reduction in S. chilikensis attachment independent of initial surface condition, while the other two strains were reduced by at least 99.7% of the original viable cell number. Our results demonstrate that CTA-4OHcinn is biocidal active and has promise as a multifunctional, environmentally sound MIC inhibitor for industrial applications. |
| first_indexed | 2024-12-17T13:58:38Z |
| format | Article |
| id | doaj.art-6b25811c51d248d894d01544463ec01a |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-17T13:58:38Z |
| publishDate | 2021-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-6b25811c51d248d894d01544463ec01a2022-12-21T21:45:50ZengNature PortfolioScientific Reports2045-23222021-08-0111111210.1038/s41598-021-94827-9Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environmentsBenjamin Tuck0Elizabeth Watkin1Maria Forsyth2Anthony Somers3Mahdi Ghorbani4Laura L. Machuca5Curtin Corrosion Centre, WA School of Mines: Minerals, Energy and Chemical Engineering, Curtin UniversityCurtin Medical School, Curtin UniversityInstitute for Frontier Materials, Deakin UniversityInstitute for Frontier Materials, Deakin UniversityInstitute for Frontier Materials, Deakin UniversityCurtin Corrosion Centre, WA School of Mines: Minerals, Energy and Chemical Engineering, Curtin UniversityAbstract Chemical biocides remain the most effective mitigation strategy against microbiologically influenced corrosion (MIC), one of the costliest and most pervasive forms of corrosion in industry. However, toxicity and environmental concerns associated with these compounds are encouraging the development of more environmentally friendly MIC inhibitors. In this study, we evaluated the antimicrobial effect of a novel, multi-functional organic corrosion inhibitor (OCI) compound, cetrimonium trans-4-hydroxy-cinnamate (CTA-4OHcinn). Attachment of three bacterial strains, Shewanella chilikensis, Pseudomonas balearica and Klebsiella pneumoniae was evaluated on wet-ground (120 grit finish) and pre-oxidised carbon steel surfaces (AISI 1030), in the presence and absence of the new OCI compound. Our study revealed that all strains preferentially attached to pre-oxidised surfaces as indicated by confocal laser scanning microscopy, scanning electron microscopy and standard colony forming unit (CFU) quantification assays. The inhibitor compound at 10 mM demonstrated 100% reduction in S. chilikensis attachment independent of initial surface condition, while the other two strains were reduced by at least 99.7% of the original viable cell number. Our results demonstrate that CTA-4OHcinn is biocidal active and has promise as a multifunctional, environmentally sound MIC inhibitor for industrial applications.https://doi.org/10.1038/s41598-021-94827-9 |
| spellingShingle | Benjamin Tuck Elizabeth Watkin Maria Forsyth Anthony Somers Mahdi Ghorbani Laura L. Machuca Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments Scientific Reports |
| title | Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments |
| title_full | Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments |
| title_fullStr | Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments |
| title_full_unstemmed | Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments |
| title_short | Evaluation of a novel, multi-functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments |
| title_sort | evaluation of a novel multi functional inhibitor compound for prevention of biofilm formation on carbon steel in marine environments |
| url | https://doi.org/10.1038/s41598-021-94827-9 |
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