Prognostic Impact of Atrial Fibrillation in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational Atherectomy
<i>Background and Objectives</i>: Although both rotational atherectomy (RA) and atrial fibrillation (AF) have a high thrombotic risk, there have been no previous studies on the prognostic impact of AF in patients who undergo percutaneous coronary intervention (PCI) using RA. Thus, the ai...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
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MDPI AG
2023-10-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/10/1808 |
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| author | Jin Jung Yeonjoo Seo Sung-Ho Her Jae-Hwan Lee Kyusup Lee Ki-Dong Yoo Keon-Woong Moon Donggyu Moon Su-Nam Lee Won-Young Jang Ik-Jun Choi Jang-Hoon Lee Sang-Rok Lee Seung-Whan Lee Kyeong-Ho Yun Hyun-Jong Lee |
| author_facet | Jin Jung Yeonjoo Seo Sung-Ho Her Jae-Hwan Lee Kyusup Lee Ki-Dong Yoo Keon-Woong Moon Donggyu Moon Su-Nam Lee Won-Young Jang Ik-Jun Choi Jang-Hoon Lee Sang-Rok Lee Seung-Whan Lee Kyeong-Ho Yun Hyun-Jong Lee |
| author_sort | Jin Jung |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Although both rotational atherectomy (RA) and atrial fibrillation (AF) have a high thrombotic risk, there have been no previous studies on the prognostic impact of AF in patients who undergo percutaneous coronary intervention (PCI) using RA. Thus, the aim of the present study was to determine the prognostic impact of AF in patients undergoing PCI using RA. <i>Materials and Methods</i>: A total of 540 patients who received PCI using RA were enrolled between January 2010 and October 2019. Patients were divided into AF and sinus rhythm groups according to the presence of AF. The primary endpoint was net adverse clinical events (NACEs) defined as a composite outcome of all-cause death, myocardial infarction, target vessel revascularization, cerebrovascular accident, or total bleeding. <i>Results</i>: Although in-hospital adverse events showed no difference between those with AF and those without AF (in-hospital events, 54 (11.0%) vs. 6 (12.2%), <i>p</i> = 0.791), AF was strongly associated with an increased risk of NACE at 3 years (NACE: hazard ratio, 1.880; 95% confidence interval, 1.096–3.227; <i>p</i> = 0.022). <i>Conclusions</i>: AF in patients who underwent PCI using RA was strongly associated with poor clinical outcomes. Thus, more attention should be paid to thrombotic and bleeding risks. |
| first_indexed | 2024-03-10T21:04:43Z |
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| language | English |
| last_indexed | 2024-03-10T21:04:43Z |
| publishDate | 2023-10-01 |
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| series | Medicina |
| spelling | doaj.art-6b273bbe87b14dfeaf7d4d51420cb5062023-11-19T17:17:33ZengMDPI AGMedicina1010-660X1648-91442023-10-015910180810.3390/medicina59101808Prognostic Impact of Atrial Fibrillation in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational AtherectomyJin Jung0Yeonjoo Seo1Sung-Ho Her2Jae-Hwan Lee3Kyusup Lee4Ki-Dong Yoo5Keon-Woong Moon6Donggyu Moon7Su-Nam Lee8Won-Young Jang9Ik-Jun Choi10Jang-Hoon Lee11Sang-Rok Lee12Seung-Whan Lee13Kyeong-Ho Yun14Hyun-Jong Lee15Department of Cardiology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of KoreaDepartment of Internal Medicine, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 07345, Republic of KoreaDepartment of Cardiology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of KoreaDepartment of Cardiology in Internal Medicine, Chungnam National University School of Medicine, Chungnam National University Sejong Hospital, Sejong 30099, Republic of KoreaDepartment of Cardiology, Daejeon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 34943, Republic of KoreaDepartment of Cardiology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of KoreaDepartment of Cardiology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of KoreaDepartment of Cardiology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of KoreaDepartment of Cardiology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of KoreaDepartment of Cardiology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul 16247, Republic of KoreaDepartment of Cardiology, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon 21431, Republic of KoreaDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu 41944, Republic of KoreaDepartment of Cardiology, Chonbuk National University Hospital, Jeonju 54907, Republic of KoreaDepartment of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of KoreaDepartment of Cardiovascular Medicine, Regional Cardiocerebrovascular Center, Wonkwang University Hospital, Iksan 54538, Republic of KoreaDepartment of Internal Medicine, Sejong General Hospital, Bucheon 14754, Republic of Korea<i>Background and Objectives</i>: Although both rotational atherectomy (RA) and atrial fibrillation (AF) have a high thrombotic risk, there have been no previous studies on the prognostic impact of AF in patients who undergo percutaneous coronary intervention (PCI) using RA. Thus, the aim of the present study was to determine the prognostic impact of AF in patients undergoing PCI using RA. <i>Materials and Methods</i>: A total of 540 patients who received PCI using RA were enrolled between January 2010 and October 2019. Patients were divided into AF and sinus rhythm groups according to the presence of AF. The primary endpoint was net adverse clinical events (NACEs) defined as a composite outcome of all-cause death, myocardial infarction, target vessel revascularization, cerebrovascular accident, or total bleeding. <i>Results</i>: Although in-hospital adverse events showed no difference between those with AF and those without AF (in-hospital events, 54 (11.0%) vs. 6 (12.2%), <i>p</i> = 0.791), AF was strongly associated with an increased risk of NACE at 3 years (NACE: hazard ratio, 1.880; 95% confidence interval, 1.096–3.227; <i>p</i> = 0.022). <i>Conclusions</i>: AF in patients who underwent PCI using RA was strongly associated with poor clinical outcomes. Thus, more attention should be paid to thrombotic and bleeding risks.https://www.mdpi.com/1648-9144/59/10/1808percutaneous coronary interventionrotational atherectomyatrial fibrillationclinical outcomescoronary artery disease |
| spellingShingle | Jin Jung Yeonjoo Seo Sung-Ho Her Jae-Hwan Lee Kyusup Lee Ki-Dong Yoo Keon-Woong Moon Donggyu Moon Su-Nam Lee Won-Young Jang Ik-Jun Choi Jang-Hoon Lee Sang-Rok Lee Seung-Whan Lee Kyeong-Ho Yun Hyun-Jong Lee Prognostic Impact of Atrial Fibrillation in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational Atherectomy Medicina percutaneous coronary intervention rotational atherectomy atrial fibrillation clinical outcomes coronary artery disease |
| title | Prognostic Impact of Atrial Fibrillation in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational Atherectomy |
| title_full | Prognostic Impact of Atrial Fibrillation in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational Atherectomy |
| title_fullStr | Prognostic Impact of Atrial Fibrillation in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational Atherectomy |
| title_full_unstemmed | Prognostic Impact of Atrial Fibrillation in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational Atherectomy |
| title_short | Prognostic Impact of Atrial Fibrillation in Patients with Heavily Calcified Coronary Artery Disease Receiving Rotational Atherectomy |
| title_sort | prognostic impact of atrial fibrillation in patients with heavily calcified coronary artery disease receiving rotational atherectomy |
| topic | percutaneous coronary intervention rotational atherectomy atrial fibrillation clinical outcomes coronary artery disease |
| url | https://www.mdpi.com/1648-9144/59/10/1808 |
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