Minimally Invasive Surgery for ICH Evacuation Combined With Deferoxamine Treatment Increased Perihematomal Claudin-5 and ZO-1 Expression Levels and Decreased BBB Permeability in Rabbits

Minimally Invasive Surgery for ICH Evacuation Combined With Deferoxamine Treatment Increased Perihematomal Claudin-5 and ZO-1 Expression Levels and Decreased BBB Permeability in Rabbits

ObjectiveTo investigate the role of minimally invasive surgery (MIS) in intracerebral hemorrhage (ICH) evacuation combined with deferoxamine (DFX) treatment on perihematomal tight junction protein (claudin-5 and ZO-1) expression levels and blood-brain barrier (BBB) permeability in rabbits.MethodsWe...

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Bibliographic Details
Main Authors: Siying Ren, Shanshan Han, Likun Wang, Yuanxin Huang, Jing Wu, Guofeng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Neurology
Subjects:
intracerebral hemorrhage
minimally invasive surgery
deferoxamine
tight junction proteins
blood-brain barrier permeability
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.835494/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2022.835494/full

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