Preparation and Characterization of Ion-Sensitive Brimonidine Tartrate In Situ Gel for Ocular Delivery

Preparation and Characterization of Ion-Sensitive Brimonidine Tartrate In Situ Gel for Ocular Delivery

Brimonidine tartrate (BRT) is a highly selective α2 adrenergic receptor agonist as treatment for patients with open angle glaucoma and high intraocular pressure. The objective of this study was to formulate an ophthalmic ion-sensitive in situ gel (ISG) of BRT to increase the retention time of the dr...

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Bibliographic Details
Main Authors:	Haonan Xu, Ye Liu, Lu Jin, Xu Chen, Xinghao Chen, Qiao Wang, Zhan Tang
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Series:	Pharmaceuticals
Subjects:	brimonidine tartrate in-situ gel ocular permeation microdialysis
Online Access:	https://www.mdpi.com/1424-8247/16/1/90

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