Bio-Mechanical Model of Osteosarcoma Tumor Microenvironment: A Porous Media Approach

Osteosarcoma is the most common malignant bone tumor in children and adolescents with a poor prognosis. To describe the progression of osteosarcoma, we expanded a system of data-driven ODE from a previous study into a system of Reaction-Diffusion-Advection (RDA) equations and coupled it with Biot eq...

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Bibliographic Details
Main Authors: Yu Hu, Navid Mohammad Mirzaei, Leili Shahriyari
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/24/6143