Exploring Parkinson’s Disease-Associated Depression: Role of Inflammation on the Noradrenergic and Serotonergic Pathways

Exploring Parkinson’s Disease-Associated Depression: Role of Inflammation on the Noradrenergic and Serotonergic Pathways

Parkinson’s disease (PD) is a multifactorial disease, with genetic and environmental factors contributing to the disease onset. Classically, PD is a movement disorder characterized by the loss of dopaminergic neurons in the nigrostriatal pathway and intraneuronal aggregates mainly constituted of the...

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Bibliographic Details
Main Authors: Tuane Bazanella Sampaio, Marissa Giovanna Schamne, Jean Rodrigo Santos, Marcelo Machado Ferro, Edmar Miyoshi, Rui Daniel Prediger
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Brain Sciences
Subjects:
Parkinson’s disease
neuroinflammation
antidepressants
locus coeruleus
raphe nuclei
Online Access:https://www.mdpi.com/2076-3425/14/1/100

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