The value of C-reactive protein and lactate in the acute abdomen in the emergency department

<p>Abstract</p> <p>Case presentation</p> <p>This report describes the presentation of three critically ill patients with non-traumatic acute abdominal pain and increased concentrations of the biomarkers C-reactive protein (CRP) and lactate. In these three patients an ex...

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Main Authors: Meyer Zainna C, Schreinemakers Jennifer MJ, van der Laan Lijckle
Format: Article
Language:English
Published: BMC 2012-07-01
Series:World Journal of Emergency Surgery
Subjects:
Online Access:http://www.wjes.org/content/7/1/22
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author Meyer Zainna C
Schreinemakers Jennifer MJ
van der Laan Lijckle
author_facet Meyer Zainna C
Schreinemakers Jennifer MJ
van der Laan Lijckle
author_sort Meyer Zainna C
collection DOAJ
description <p>Abstract</p> <p>Case presentation</p> <p>This report describes the presentation of three critically ill patients with non-traumatic acute abdominal pain and increased concentrations of the biomarkers C-reactive protein (CRP) and lactate. In these three patients an exploratory laparotomy was carried out. Remarkably, the laparotomy showed no intra-abdominal abnormalities. We discuss the usefulness of these biomarkers in practice and their influence on establishing a diagnose and making a decision to perform an intervention.</p> <p>Conclusion</p> <p>We conclude that biomarkers lactate and CRP in patients with acute abdominal pain should only be used in adjunct to the history and clinical findings, as they are not specific and can be misleading in establishing a diagnosis. In addition, relying on these biomarkers may contribute to more diagnostic examinations and/or unnecessary invasive interventions (for example laparotomy).</p>
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spelling doaj.art-6b2f19f9f7434e5b91f0d661be8b35ad2022-12-22T01:18:42ZengBMCWorld Journal of Emergency Surgery1749-79222012-07-01712210.1186/1749-7922-7-22The value of C-reactive protein and lactate in the acute abdomen in the emergency departmentMeyer Zainna CSchreinemakers Jennifer MJvan der Laan Lijckle<p>Abstract</p> <p>Case presentation</p> <p>This report describes the presentation of three critically ill patients with non-traumatic acute abdominal pain and increased concentrations of the biomarkers C-reactive protein (CRP) and lactate. In these three patients an exploratory laparotomy was carried out. Remarkably, the laparotomy showed no intra-abdominal abnormalities. We discuss the usefulness of these biomarkers in practice and their influence on establishing a diagnose and making a decision to perform an intervention.</p> <p>Conclusion</p> <p>We conclude that biomarkers lactate and CRP in patients with acute abdominal pain should only be used in adjunct to the history and clinical findings, as they are not specific and can be misleading in establishing a diagnosis. In addition, relying on these biomarkers may contribute to more diagnostic examinations and/or unnecessary invasive interventions (for example laparotomy).</p>http://www.wjes.org/content/7/1/22Acute abdomenC-reactive proteinLactate
spellingShingle Meyer Zainna C
Schreinemakers Jennifer MJ
van der Laan Lijckle
The value of C-reactive protein and lactate in the acute abdomen in the emergency department
World Journal of Emergency Surgery
Acute abdomen
C-reactive protein
Lactate
title The value of C-reactive protein and lactate in the acute abdomen in the emergency department
title_full The value of C-reactive protein and lactate in the acute abdomen in the emergency department
title_fullStr The value of C-reactive protein and lactate in the acute abdomen in the emergency department
title_full_unstemmed The value of C-reactive protein and lactate in the acute abdomen in the emergency department
title_short The value of C-reactive protein and lactate in the acute abdomen in the emergency department
title_sort value of c reactive protein and lactate in the acute abdomen in the emergency department
topic Acute abdomen
C-reactive protein
Lactate
url http://www.wjes.org/content/7/1/22
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