Advancing dental implants: Bioactive and therapeutic modifications of zirconia
Zirconium-based implants have gained popularity in the dental implant field owing to their corrosion resistance and biocompatibility, attributed to the formation of a native zirconia (ZrO2) film. However, enhanced bioactivity and local therapy from such implants are desirable to enable the earlier e...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2022-07-01
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| Series: | Bioactive Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452199X21004710 |
| _version_ | 1797204941687750656 |
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| author | Divya Chopra Anjana Jayasree Tianqi Guo Karan Gulati Sašo Ivanovski |
| author_facet | Divya Chopra Anjana Jayasree Tianqi Guo Karan Gulati Sašo Ivanovski |
| author_sort | Divya Chopra |
| collection | DOAJ |
| description | Zirconium-based implants have gained popularity in the dental implant field owing to their corrosion resistance and biocompatibility, attributed to the formation of a native zirconia (ZrO2) film. However, enhanced bioactivity and local therapy from such implants are desirable to enable the earlier establishment and improved long-term maintenance of implant integration, especially in compromised patient conditions. As a result, surface modification of zirconium-based implants have been performed using various physical, chemical and biological techniques at the macro-, micro-, and nano-scales. In this extensive review, we discuss and detail the development of Zr implants covering the spectrum from past and present advancements to future perspectives, arriving at the next generation of highly bioactive and therapeutic nano-engineered Zr-based implants. The review provides in-depth knowledge of the bioactive/therapeutic value of surface modification of Zr implants in dental implant applications focusing on clinical translation. |
| first_indexed | 2024-04-24T08:43:14Z |
| format | Article |
| id | doaj.art-6b2fadacb5154baa8bb6f87f20d8e7a7 |
| institution | Directory Open Access Journal |
| issn | 2452-199X |
| language | English |
| last_indexed | 2024-04-24T08:43:14Z |
| publishDate | 2022-07-01 |
| publisher | KeAi Communications Co., Ltd. |
| record_format | Article |
| series | Bioactive Materials |
| spelling | doaj.art-6b2fadacb5154baa8bb6f87f20d8e7a72024-04-16T14:37:44ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2022-07-0113161178Advancing dental implants: Bioactive and therapeutic modifications of zirconiaDivya Chopra0Anjana Jayasree1Tianqi Guo2Karan Gulati3Sašo Ivanovski4The University of Queensland, School of Dentistry, Herston QLD, 4006, AustraliaThe University of Queensland, School of Dentistry, Herston QLD, 4006, AustraliaThe University of Queensland, School of Dentistry, Herston QLD, 4006, AustraliaCorresponding authors. School of Dentistry, University of Queensland, 288 Herston Road, Herston QLD, 4006, Australia.; The University of Queensland, School of Dentistry, Herston QLD, 4006, AustraliaCorresponding authors. School of Dentistry, University of Queensland, 288 Herston Road, Herston QLD, 4006, Australia.; The University of Queensland, School of Dentistry, Herston QLD, 4006, AustraliaZirconium-based implants have gained popularity in the dental implant field owing to their corrosion resistance and biocompatibility, attributed to the formation of a native zirconia (ZrO2) film. However, enhanced bioactivity and local therapy from such implants are desirable to enable the earlier establishment and improved long-term maintenance of implant integration, especially in compromised patient conditions. As a result, surface modification of zirconium-based implants have been performed using various physical, chemical and biological techniques at the macro-, micro-, and nano-scales. In this extensive review, we discuss and detail the development of Zr implants covering the spectrum from past and present advancements to future perspectives, arriving at the next generation of highly bioactive and therapeutic nano-engineered Zr-based implants. The review provides in-depth knowledge of the bioactive/therapeutic value of surface modification of Zr implants in dental implant applications focusing on clinical translation.http://www.sciencedirect.com/science/article/pii/S2452199X21004710ZirconiumZirconiaImplantsSurface modificationOsseointegrationBioactivity |
| spellingShingle | Divya Chopra Anjana Jayasree Tianqi Guo Karan Gulati Sašo Ivanovski Advancing dental implants: Bioactive and therapeutic modifications of zirconia Bioactive Materials Zirconium Zirconia Implants Surface modification Osseointegration Bioactivity |
| title | Advancing dental implants: Bioactive and therapeutic modifications of zirconia |
| title_full | Advancing dental implants: Bioactive and therapeutic modifications of zirconia |
| title_fullStr | Advancing dental implants: Bioactive and therapeutic modifications of zirconia |
| title_full_unstemmed | Advancing dental implants: Bioactive and therapeutic modifications of zirconia |
| title_short | Advancing dental implants: Bioactive and therapeutic modifications of zirconia |
| title_sort | advancing dental implants bioactive and therapeutic modifications of zirconia |
| topic | Zirconium Zirconia Implants Surface modification Osseointegration Bioactivity |
| url | http://www.sciencedirect.com/science/article/pii/S2452199X21004710 |
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