Evaluation of Antioxidant and Antibacterial Activities of Apis florea Fabricius (Hymenoptera: Apidae) Honey on Helicobacter pylori
Iranian men are at risk of developing gastrointestinal cancer caused by H. pylori. It is very imperative to find effective methods to control this bacterium as there are currently no very effective treatments for it. Honey has been shown to have antimicrobial properties against various pathogens. Th...
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| Format: | Article |
| Language: | English |
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Ferdowsi University of Mashhad
2023-07-01
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| Series: | مجله پژوهشهای علوم و صنایع غذایی ایران |
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| Online Access: | https://ifstrj.um.ac.ir/article_44060_be5760964ace75fd416e9a90ee0850ec.pdf |
| _version_ | 1827777200125902848 |
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| author | Sh. Parichehreh Gh. Tahmasbi M. Eslampanah P. Khaki |
| author_facet | Sh. Parichehreh Gh. Tahmasbi M. Eslampanah P. Khaki |
| author_sort | Sh. Parichehreh |
| collection | DOAJ |
| description | Iranian men are at risk of developing gastrointestinal cancer caused by H. pylori. It is very imperative to find effective methods to control this bacterium as there are currently no very effective treatments for it. Honey has been shown to have antimicrobial properties against various pathogens. This study analyzed 15 honey samples from A. florea bees, collected from different floral and geographical origins, for their antimicrobial efficacy against H. pylori. Using atomic absorption measurements, the honey samples were also tested for their phenolic and flavonoid content, protein concentration, and mineral content. Antioxidant activity was determined using the FRAP, DPPH, and ABTS methods. The antibacterial activity of honey samples was investigated both in-vitro and in-vivo in the gastrointestinal tract of mice. Statistical analysis revealed a significant positive correlation between antioxidant activity and antibacterial activity. All honey samples showed antimicrobial activity in-vitro, among which jujube honey from Bushehr exhibiting the highest activity. Differences in antioxidant and antimicrobial activities were likely due to the flora of the plants and the geographic region from which the honey was harvested. Based on these results, A. florea honey may be used in the prevention and treatment of H. pylori-associated infections and inflammation of the gastrointestinal tract. This feature can be applied to the control of Helicobacter pylori along with other available measures. |
| first_indexed | 2024-03-11T14:15:13Z |
| format | Article |
| id | doaj.art-6b3154a445af4ef086138ec0a031dd5a |
| institution | Directory Open Access Journal |
| issn | 1735-4161 2228-5415 |
| language | English |
| last_indexed | 2024-03-11T14:15:13Z |
| publishDate | 2023-07-01 |
| publisher | Ferdowsi University of Mashhad |
| record_format | Article |
| series | مجله پژوهشهای علوم و صنایع غذایی ایران |
| spelling | doaj.art-6b3154a445af4ef086138ec0a031dd5a2023-11-01T07:08:35ZengFerdowsi University of Mashhadمجله پژوهشهای علوم و صنایع غذایی ایران1735-41612228-54152023-07-01193496310.22067/ifstrj.2023.81933.124844060Evaluation of Antioxidant and Antibacterial Activities of Apis florea Fabricius (Hymenoptera: Apidae) Honey on Helicobacter pyloriSh. Parichehreh0Gh. Tahmasbi1M. Eslampanah2P. Khaki3Department of Honeybee, Animal Science Research Institute of Iran, Agricultural Research Education and Extension Organization (AREEO), Karaj, IranDepartment of Honeybee, Animal Science Research Institute of Iran, Agricultural Research Education and Extension Organization (AREEO), Karaj, IranAgricultural Research Education and Extension Organization (AREEO), Karaj, Iran, respectively. (*- Corresponding Author Email: Sh.pariichehreh@gmail.com) 3 and 4- Ph.D. Graduate and Associate Professor, Department of Microbiology, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), KarajDepartment of Microbiology, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, IranIranian men are at risk of developing gastrointestinal cancer caused by H. pylori. It is very imperative to find effective methods to control this bacterium as there are currently no very effective treatments for it. Honey has been shown to have antimicrobial properties against various pathogens. This study analyzed 15 honey samples from A. florea bees, collected from different floral and geographical origins, for their antimicrobial efficacy against H. pylori. Using atomic absorption measurements, the honey samples were also tested for their phenolic and flavonoid content, protein concentration, and mineral content. Antioxidant activity was determined using the FRAP, DPPH, and ABTS methods. The antibacterial activity of honey samples was investigated both in-vitro and in-vivo in the gastrointestinal tract of mice. Statistical analysis revealed a significant positive correlation between antioxidant activity and antibacterial activity. All honey samples showed antimicrobial activity in-vitro, among which jujube honey from Bushehr exhibiting the highest activity. Differences in antioxidant and antimicrobial activities were likely due to the flora of the plants and the geographic region from which the honey was harvested. Based on these results, A. florea honey may be used in the prevention and treatment of H. pylori-associated infections and inflammation of the gastrointestinal tract. This feature can be applied to the control of Helicobacter pylori along with other available measures.https://ifstrj.um.ac.ir/article_44060_be5760964ace75fd416e9a90ee0850ec.pdfantioxidant activityantimicrobial activitieshoneyh. pylori |
| spellingShingle | Sh. Parichehreh Gh. Tahmasbi M. Eslampanah P. Khaki Evaluation of Antioxidant and Antibacterial Activities of Apis florea Fabricius (Hymenoptera: Apidae) Honey on Helicobacter pylori مجله پژوهشهای علوم و صنایع غذایی ایران antioxidant activity antimicrobial activities honey h. pylori |
| title | Evaluation of Antioxidant and Antibacterial Activities of Apis florea Fabricius (Hymenoptera: Apidae) Honey on Helicobacter pylori |
| title_full | Evaluation of Antioxidant and Antibacterial Activities of Apis florea Fabricius (Hymenoptera: Apidae) Honey on Helicobacter pylori |
| title_fullStr | Evaluation of Antioxidant and Antibacterial Activities of Apis florea Fabricius (Hymenoptera: Apidae) Honey on Helicobacter pylori |
| title_full_unstemmed | Evaluation of Antioxidant and Antibacterial Activities of Apis florea Fabricius (Hymenoptera: Apidae) Honey on Helicobacter pylori |
| title_short | Evaluation of Antioxidant and Antibacterial Activities of Apis florea Fabricius (Hymenoptera: Apidae) Honey on Helicobacter pylori |
| title_sort | evaluation of antioxidant and antibacterial activities of apis florea fabricius hymenoptera apidae honey on helicobacter pylori |
| topic | antioxidant activity antimicrobial activities honey h. pylori |
| url | https://ifstrj.um.ac.ir/article_44060_be5760964ace75fd416e9a90ee0850ec.pdf |
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