Psychiatric manifestations of systemic lupus erythematosus: A brief review with two case-reports

Neuropsychiatric systemic lupus erythematosus is a severe neurological and psychiatric manifestation following systemic lupus erythematosus. Neuropsychiatric systemic lupus erythematosus is a global concern with limited data on its impact on quality of life in Africa. Furthermore, there is a lack of...

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Main Authors: Faiz Mohammed Kassim, Dureti Kassim Wordefo, Mahlet Berhanu, Surafel Worku Megersa, Selamawit Alemayehu Tessema
Format: Article
Language:English
Published: SAGE Publishing 2024-02-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X241229010
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author Faiz Mohammed Kassim
Dureti Kassim Wordefo
Mahlet Berhanu
Surafel Worku Megersa
Selamawit Alemayehu Tessema
author_facet Faiz Mohammed Kassim
Dureti Kassim Wordefo
Mahlet Berhanu
Surafel Worku Megersa
Selamawit Alemayehu Tessema
author_sort Faiz Mohammed Kassim
collection DOAJ
description Neuropsychiatric systemic lupus erythematosus is a severe neurological and psychiatric manifestation following systemic lupus erythematosus. Neuropsychiatric systemic lupus erythematosus is a global concern with limited data on its impact on quality of life in Africa. Furthermore, there is a lack of published research on neuropsychiatric systemic lupus erythematosus in Ethiopia. In this article, we present two case reports of Ethiopian patients with systemic lupus erythematosus and neuropsychiatric systemic lupus erythematosus, highlighting the challenges of diagnosing neuropsychiatric systemic lupus erythematosus worldwide. Although the patients were treated with alternative pharmacological agents based on available medications, interdisciplinary collaboration between psychologists, psychiatrists, neurologists, and internists is necessary to decrease the burden of systemic lupus erythematosus patients with neuropsychiatric manifestations. Overall, symptomatic therapy for neuropsychiatric systemic lupus erythematosus in developing countries is a good approach until future evidence-based pharmacotherapy is developed.
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spelling doaj.art-6b3571e8359142c8aa581a0a9d3329062024-02-03T10:03:38ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2024-02-011210.1177/2050313X241229010Psychiatric manifestations of systemic lupus erythematosus: A brief review with two case-reportsFaiz Mohammed KassimDureti Kassim WordefoMahlet BerhanuSurafel Worku MegersaSelamawit Alemayehu TessemaNeuropsychiatric systemic lupus erythematosus is a severe neurological and psychiatric manifestation following systemic lupus erythematosus. Neuropsychiatric systemic lupus erythematosus is a global concern with limited data on its impact on quality of life in Africa. Furthermore, there is a lack of published research on neuropsychiatric systemic lupus erythematosus in Ethiopia. In this article, we present two case reports of Ethiopian patients with systemic lupus erythematosus and neuropsychiatric systemic lupus erythematosus, highlighting the challenges of diagnosing neuropsychiatric systemic lupus erythematosus worldwide. Although the patients were treated with alternative pharmacological agents based on available medications, interdisciplinary collaboration between psychologists, psychiatrists, neurologists, and internists is necessary to decrease the burden of systemic lupus erythematosus patients with neuropsychiatric manifestations. Overall, symptomatic therapy for neuropsychiatric systemic lupus erythematosus in developing countries is a good approach until future evidence-based pharmacotherapy is developed.https://doi.org/10.1177/2050313X241229010
spellingShingle Faiz Mohammed Kassim
Dureti Kassim Wordefo
Mahlet Berhanu
Surafel Worku Megersa
Selamawit Alemayehu Tessema
Psychiatric manifestations of systemic lupus erythematosus: A brief review with two case-reports
SAGE Open Medical Case Reports
title Psychiatric manifestations of systemic lupus erythematosus: A brief review with two case-reports
title_full Psychiatric manifestations of systemic lupus erythematosus: A brief review with two case-reports
title_fullStr Psychiatric manifestations of systemic lupus erythematosus: A brief review with two case-reports
title_full_unstemmed Psychiatric manifestations of systemic lupus erythematosus: A brief review with two case-reports
title_short Psychiatric manifestations of systemic lupus erythematosus: A brief review with two case-reports
title_sort psychiatric manifestations of systemic lupus erythematosus a brief review with two case reports
url https://doi.org/10.1177/2050313X241229010
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