The Use of Machine Learning Algorithms in the Evaluation of the Effectiveness of Resynchronization Therapy

Background: Cardiovascular disease remains the leading cause of death in the European Union and worldwide. Constant improvement in cardiac care is leading to an increased number of patients with heart failure, which is a challenging condition in terms of clinical management. Cardiac resynchronizatio...

Full description

Bibliographic Details
Main Authors: Bartosz Krzowski, Jakub Rokicki, Renata Główczyńska, Nikola Fajkis-Zajączkowska, Katarzyna Barczewska, Mariusz Mąsior, Marcin Grabowski, Paweł Balsam
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/9/1/17
_version_ 1797493103177760768
author Bartosz Krzowski
Jakub Rokicki
Renata Główczyńska
Nikola Fajkis-Zajączkowska
Katarzyna Barczewska
Mariusz Mąsior
Marcin Grabowski
Paweł Balsam
author_facet Bartosz Krzowski
Jakub Rokicki
Renata Główczyńska
Nikola Fajkis-Zajączkowska
Katarzyna Barczewska
Mariusz Mąsior
Marcin Grabowski
Paweł Balsam
author_sort Bartosz Krzowski
collection DOAJ
description Background: Cardiovascular disease remains the leading cause of death in the European Union and worldwide. Constant improvement in cardiac care is leading to an increased number of patients with heart failure, which is a challenging condition in terms of clinical management. Cardiac resynchronization therapy is becoming more popular because of its grounded position in guidelines and clinical practice. However, some patients do not respond to treatment as expected. One way of assessing cardiac resynchronization therapy is with ECG analysis. Artificial intelligence is increasing in terms of everyday usability due to the possibility of everyday workflow improvement and, as a result, shortens the time required for diagnosis. A special area of artificial intelligence is machine learning. AI algorithms learn on their own based on implemented data. The aim of this study was to evaluate using artificial intelligence algorithms for detecting inadequate resynchronization therapy. Methods: A total of 1241 ECG tracings were collected from 547 cardiac department patients. All ECG signals were analyzed by three independent cardiologists. Every signal event (QRS-complex) and rhythm was manually classified by the medical team and fully reviewed by additional cardiologists. The results were divided into two parts: 80% of the results were used to train the algorithm, and 20% were used for the test (Cardiomatics, Cracow, Poland). Results: The required level of detection sensitivity of effective cardiac resynchronization therapy stimulation was achieved: 99.2% with a precision of 92.4%. Conclusions: Artificial intelligence algorithms can be a useful tool in assessing the effectiveness of resynchronization therapy.
first_indexed 2024-03-10T01:15:12Z
format Article
id doaj.art-6b383e387bfe4c41bcbd1b94db332089
institution Directory Open Access Journal
issn 2308-3425
language English
last_indexed 2024-03-10T01:15:12Z
publishDate 2022-01-01
publisher MDPI AG
record_format Article
series Journal of Cardiovascular Development and Disease
spelling doaj.art-6b383e387bfe4c41bcbd1b94db3320892023-11-23T14:11:09ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252022-01-01911710.3390/jcdd9010017The Use of Machine Learning Algorithms in the Evaluation of the Effectiveness of Resynchronization TherapyBartosz Krzowski0Jakub Rokicki1Renata Główczyńska2Nikola Fajkis-Zajączkowska3Katarzyna Barczewska4Mariusz Mąsior5Marcin Grabowski6Paweł Balsam71st Department of Cardiology, Medical University of Warsaw, 02-097 Warsaw, Poland1st Department of Cardiology, Medical University of Warsaw, 02-097 Warsaw, Poland1st Department of Cardiology, Medical University of Warsaw, 02-097 Warsaw, PolandCardiomatics, 31-339 Cracow, PolandCardiomatics, 31-339 Cracow, PolandCardiomatics, 31-339 Cracow, Poland1st Department of Cardiology, Medical University of Warsaw, 02-097 Warsaw, Poland1st Department of Cardiology, Medical University of Warsaw, 02-097 Warsaw, PolandBackground: Cardiovascular disease remains the leading cause of death in the European Union and worldwide. Constant improvement in cardiac care is leading to an increased number of patients with heart failure, which is a challenging condition in terms of clinical management. Cardiac resynchronization therapy is becoming more popular because of its grounded position in guidelines and clinical practice. However, some patients do not respond to treatment as expected. One way of assessing cardiac resynchronization therapy is with ECG analysis. Artificial intelligence is increasing in terms of everyday usability due to the possibility of everyday workflow improvement and, as a result, shortens the time required for diagnosis. A special area of artificial intelligence is machine learning. AI algorithms learn on their own based on implemented data. The aim of this study was to evaluate using artificial intelligence algorithms for detecting inadequate resynchronization therapy. Methods: A total of 1241 ECG tracings were collected from 547 cardiac department patients. All ECG signals were analyzed by three independent cardiologists. Every signal event (QRS-complex) and rhythm was manually classified by the medical team and fully reviewed by additional cardiologists. The results were divided into two parts: 80% of the results were used to train the algorithm, and 20% were used for the test (Cardiomatics, Cracow, Poland). Results: The required level of detection sensitivity of effective cardiac resynchronization therapy stimulation was achieved: 99.2% with a precision of 92.4%. Conclusions: Artificial intelligence algorithms can be a useful tool in assessing the effectiveness of resynchronization therapy.https://www.mdpi.com/2308-3425/9/1/17artificial intelligenceheart failurecardiac resynchronization therapy
spellingShingle Bartosz Krzowski
Jakub Rokicki
Renata Główczyńska
Nikola Fajkis-Zajączkowska
Katarzyna Barczewska
Mariusz Mąsior
Marcin Grabowski
Paweł Balsam
The Use of Machine Learning Algorithms in the Evaluation of the Effectiveness of Resynchronization Therapy
Journal of Cardiovascular Development and Disease
artificial intelligence
heart failure
cardiac resynchronization therapy
title The Use of Machine Learning Algorithms in the Evaluation of the Effectiveness of Resynchronization Therapy
title_full The Use of Machine Learning Algorithms in the Evaluation of the Effectiveness of Resynchronization Therapy
title_fullStr The Use of Machine Learning Algorithms in the Evaluation of the Effectiveness of Resynchronization Therapy
title_full_unstemmed The Use of Machine Learning Algorithms in the Evaluation of the Effectiveness of Resynchronization Therapy
title_short The Use of Machine Learning Algorithms in the Evaluation of the Effectiveness of Resynchronization Therapy
title_sort use of machine learning algorithms in the evaluation of the effectiveness of resynchronization therapy
topic artificial intelligence
heart failure
cardiac resynchronization therapy
url https://www.mdpi.com/2308-3425/9/1/17
work_keys_str_mv AT bartoszkrzowski theuseofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT jakubrokicki theuseofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT renatagłowczynska theuseofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT nikolafajkiszajaczkowska theuseofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT katarzynabarczewska theuseofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT mariuszmasior theuseofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT marcingrabowski theuseofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT pawełbalsam theuseofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT bartoszkrzowski useofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT jakubrokicki useofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT renatagłowczynska useofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT nikolafajkiszajaczkowska useofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT katarzynabarczewska useofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT mariuszmasior useofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT marcingrabowski useofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy
AT pawełbalsam useofmachinelearningalgorithmsintheevaluationoftheeffectivenessofresynchronizationtherapy