Case report: Castleman’s disease involving the renal sinus resembling renal cell carcinoma
IntroductionCastleman's disease (CD) is a rare benign lymphoproliferative disease that frequently involves the mediastinal thorax and the neck lymph nodes. It rarely affects extrathoracic presentations, with even fewer presentations in the renal sinus.Patient concernsIn this report, we present...
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| Format: | Article |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1001350/full |
| _version_ | 1798004501280456704 |
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| author | Enlong Zhang Enlong Zhang Yuan Li Ning Lang |
| author_facet | Enlong Zhang Enlong Zhang Yuan Li Ning Lang |
| author_sort | Enlong Zhang |
| collection | DOAJ |
| description | IntroductionCastleman's disease (CD) is a rare benign lymphoproliferative disease that frequently involves the mediastinal thorax and the neck lymph nodes. It rarely affects extrathoracic presentations, with even fewer presentations in the renal sinus.Patient concernsIn this report, we present a case of a 40-year-old woman with no significant past medical history who presented Castleman's disease arising in the renal sinus.Diagnosis and interventionsThe patient visited our hospital with the chief complaint of left renal sinus lesion after renal ultrasonography by regular physical examination. Subsequent abdominal computed tomography urography revealed a soft tissue mass with heterogeneous obvious enhancement in the sinus of the left kidney, which was suspected to be a renal malignant tumor. Hence, the patient underwent a left radical nephrectomy. Histological examination revealed hyperplastic lymphoid follicles in the renal sinus and was finally diagnosed as Castleman's disease of the hyaline vascular type.OutcomesFive days after the surgery procedure, the patient was discharged.ConclusionDue to the low incidence of Castleman's disease in renal sinus, there is a strong likelihood of missed diagnosis or misdiagnosis, and it is, therefore, important to be aware of the risk. Heightened awareness of this disease and its radiographic manifestations may prompt consideration of this diagnosis. Therefore, we explored the radiologic findings to find out some radiologic features suggesting this condition to help clinicians to schedule nephron-sparing surgery in the future. |
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| id | doaj.art-6b38bcc198264f0793a716c4e55f57a2 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-11T12:25:47Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Surgery |
| spelling | doaj.art-6b38bcc198264f0793a716c4e55f57a22022-12-22T04:23:57ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-09-01910.3389/fsurg.2022.10013501001350Case report: Castleman’s disease involving the renal sinus resembling renal cell carcinomaEnlong Zhang0Enlong Zhang1Yuan Li2Ning Lang3Department of Radiology, Peking University Third Hospital, Beijing, ChinaDepartment of Radiology, Peking University International Hospital, Beijing, ChinaDepartment of Radiology, Peking University Third Hospital, Beijing, ChinaDepartment of Radiology, Peking University Third Hospital, Beijing, ChinaIntroductionCastleman's disease (CD) is a rare benign lymphoproliferative disease that frequently involves the mediastinal thorax and the neck lymph nodes. It rarely affects extrathoracic presentations, with even fewer presentations in the renal sinus.Patient concernsIn this report, we present a case of a 40-year-old woman with no significant past medical history who presented Castleman's disease arising in the renal sinus.Diagnosis and interventionsThe patient visited our hospital with the chief complaint of left renal sinus lesion after renal ultrasonography by regular physical examination. Subsequent abdominal computed tomography urography revealed a soft tissue mass with heterogeneous obvious enhancement in the sinus of the left kidney, which was suspected to be a renal malignant tumor. Hence, the patient underwent a left radical nephrectomy. Histological examination revealed hyperplastic lymphoid follicles in the renal sinus and was finally diagnosed as Castleman's disease of the hyaline vascular type.OutcomesFive days after the surgery procedure, the patient was discharged.ConclusionDue to the low incidence of Castleman's disease in renal sinus, there is a strong likelihood of missed diagnosis or misdiagnosis, and it is, therefore, important to be aware of the risk. Heightened awareness of this disease and its radiographic manifestations may prompt consideration of this diagnosis. Therefore, we explored the radiologic findings to find out some radiologic features suggesting this condition to help clinicians to schedule nephron-sparing surgery in the future.https://www.frontiersin.org/articles/10.3389/fsurg.2022.1001350/fullhyaline vascular typerenal sinuscomputed tomography urographycase reportCastleman disease |
| spellingShingle | Enlong Zhang Enlong Zhang Yuan Li Ning Lang Case report: Castleman’s disease involving the renal sinus resembling renal cell carcinoma Frontiers in Surgery hyaline vascular type renal sinus computed tomography urography case report Castleman disease |
| title | Case report: Castleman’s disease involving the renal sinus resembling renal cell carcinoma |
| title_full | Case report: Castleman’s disease involving the renal sinus resembling renal cell carcinoma |
| title_fullStr | Case report: Castleman’s disease involving the renal sinus resembling renal cell carcinoma |
| title_full_unstemmed | Case report: Castleman’s disease involving the renal sinus resembling renal cell carcinoma |
| title_short | Case report: Castleman’s disease involving the renal sinus resembling renal cell carcinoma |
| title_sort | case report castleman s disease involving the renal sinus resembling renal cell carcinoma |
| topic | hyaline vascular type renal sinus computed tomography urography case report Castleman disease |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1001350/full |
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