Importance of Long-term EEG in Seizure-free Patients with Normal Routine EEG
Objective:Withdrawal of anti-seizure medicine (ASM) may be considered in epilepsy patients when seizure control is achieved. Predicting the risk of recurrence after discontinuing ASM. We compared routine electroencephalography (EEG) and long-term EEG (LTEEG) findings in seizure-free epilepsy patient...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2023-09-01
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| Series: | Archives of Epilepsy |
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| Online Access: |
http://archepilepsy.org/archives/archive-detail/article-preview/mportance-of-long-term-eeg-in-seizure-free-patient/62171
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| author | Ayten Ceyhan Dirican Belgin Mutluay Fulya Eren Hayrunisa Dilek Ataklı |
| author_facet | Ayten Ceyhan Dirican Belgin Mutluay Fulya Eren Hayrunisa Dilek Ataklı |
| author_sort | Ayten Ceyhan Dirican |
| collection | DOAJ |
| description | Objective:Withdrawal of anti-seizure medicine (ASM) may be considered in epilepsy patients when seizure control is achieved. Predicting the risk of recurrence after discontinuing ASM. We compared routine electroencephalography (EEG) and long-term EEG (LTEEG) findings in seizure-free epilepsy patients with planned drug discontinuation. Hence, we aimed to emphasize the relationship between interictal electrophysiological findings and clinical features to assess the superiority of LTEEG over routine EEG in medication termination.Methods:Fifty-eight patients diagnosed with epilepsy and under the follow-up epilepsy outpatient clinics of our tertiary center with normal EEG and at least a two-year seizure-free period were included. LTEEG was performed in all these patients. Age, sex, seizure onset age, type and frequency, risk factors for epilepsy, anti-seizure medications, neurological examination, and electrophysiological and magnetic resonance imaging (MRI) findings were retrospectively recorded.Results:The study group consisted of 36 females (62.1%) and 22 males (37.9%). Their mean age was 38.67 (21-70) years. The mean duration of seizure freedom was 4.8 years. Neurological examination was abnormal in 9 patients, and MRI detected an anomaly in 22 patients (37.9%). Epileptiform anomalies on LTEEG were observed in 27 (46.6%) of 58 patients. LTEEG anomalies and seizure frequency were correlated with a statistically significant relationship.Conclusion:LTEEG may reveal interictal epileptiform anomalies even in patients with long-term seizure-free epilepsy with a normal routine EEG. On the basis of our results, we would like to emphasize the value of LTEEG to reevaluate a better treatment strategy in seizure-free patients. |
| first_indexed | 2024-03-11T21:50:30Z |
| format | Article |
| id | doaj.art-6b3dee97285e433dbcdd5da7366dc0e7 |
| institution | Directory Open Access Journal |
| issn | 2792-0550 |
| language | English |
| last_indexed | 2024-03-11T21:50:30Z |
| publishDate | 2023-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Archives of Epilepsy |
| spelling | doaj.art-6b3dee97285e433dbcdd5da7366dc0e72023-09-26T09:01:54ZengGalenos YayineviArchives of Epilepsy2792-05502023-09-01293919510.4274/ArchEpilepsy.2023.2307813049054Importance of Long-term EEG in Seizure-free Patients with Normal Routine EEGAyten Ceyhan Dirican0Belgin Mutluay1Fulya Eren2Hayrunisa Dilek Ataklı3 University of Health Sciences Turkey, Bakırköy Prof. Dr. Mazhar Osman Mental Health and Neurology Training and Research Hospital, İstanbul, Turkey University of Health Sciences Turkey, Bakırköy Prof. Dr. Mazhar Osman Mental Health and Neurology Training and Research Hospital, İstanbul, Turkey University of Health Sciences Turkey, Bakırköy Prof. Dr. Mazhar Osman Mental Health and Neurology Training and Research Hospital, İstanbul, Turkey University of Health Sciences Turkey, Bakırköy Prof. Dr. Mazhar Osman Mental Health and Neurology Training and Research Hospital, İstanbul, Turkey Objective:Withdrawal of anti-seizure medicine (ASM) may be considered in epilepsy patients when seizure control is achieved. Predicting the risk of recurrence after discontinuing ASM. We compared routine electroencephalography (EEG) and long-term EEG (LTEEG) findings in seizure-free epilepsy patients with planned drug discontinuation. Hence, we aimed to emphasize the relationship between interictal electrophysiological findings and clinical features to assess the superiority of LTEEG over routine EEG in medication termination.Methods:Fifty-eight patients diagnosed with epilepsy and under the follow-up epilepsy outpatient clinics of our tertiary center with normal EEG and at least a two-year seizure-free period were included. LTEEG was performed in all these patients. Age, sex, seizure onset age, type and frequency, risk factors for epilepsy, anti-seizure medications, neurological examination, and electrophysiological and magnetic resonance imaging (MRI) findings were retrospectively recorded.Results:The study group consisted of 36 females (62.1%) and 22 males (37.9%). Their mean age was 38.67 (21-70) years. The mean duration of seizure freedom was 4.8 years. Neurological examination was abnormal in 9 patients, and MRI detected an anomaly in 22 patients (37.9%). Epileptiform anomalies on LTEEG were observed in 27 (46.6%) of 58 patients. LTEEG anomalies and seizure frequency were correlated with a statistically significant relationship.Conclusion:LTEEG may reveal interictal epileptiform anomalies even in patients with long-term seizure-free epilepsy with a normal routine EEG. On the basis of our results, we would like to emphasize the value of LTEEG to reevaluate a better treatment strategy in seizure-free patients. http://archepilepsy.org/archives/archive-detail/article-preview/mportance-of-long-term-eeg-in-seizure-free-patient/62171 seizure-freeroutine eeglong-term eeg |
| spellingShingle | Ayten Ceyhan Dirican Belgin Mutluay Fulya Eren Hayrunisa Dilek Ataklı Importance of Long-term EEG in Seizure-free Patients with Normal Routine EEG Archives of Epilepsy seizure-free routine eeg long-term eeg |
| title | Importance of Long-term EEG in Seizure-free Patients with Normal Routine EEG |
| title_full | Importance of Long-term EEG in Seizure-free Patients with Normal Routine EEG |
| title_fullStr | Importance of Long-term EEG in Seizure-free Patients with Normal Routine EEG |
| title_full_unstemmed | Importance of Long-term EEG in Seizure-free Patients with Normal Routine EEG |
| title_short | Importance of Long-term EEG in Seizure-free Patients with Normal Routine EEG |
| title_sort | importance of long term eeg in seizure free patients with normal routine eeg |
| topic | seizure-free routine eeg long-term eeg |
| url |
http://archepilepsy.org/archives/archive-detail/article-preview/mportance-of-long-term-eeg-in-seizure-free-patient/62171
|
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