Late-onset bleb-associated endophthalmitis and continuous positive airway pressure
Purpose: To raise awareness of a possible association between continuous positive airway pressure (CPAP) devices and postoperative bleb-related infection. Observations: A 57-year old patient on CPAP presented with unilateral bleb-associated endophthalmitis 32 months after routine ExPress Trabeculect...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-06-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S245199361730169X |
| _version_ | 1818511099540013056 |
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| author | Erich J. Berg John B. Davies Mark R. Buboltz Thomas W. Samuelson |
| author_facet | Erich J. Berg John B. Davies Mark R. Buboltz Thomas W. Samuelson |
| author_sort | Erich J. Berg |
| collection | DOAJ |
| description | Purpose: To raise awareness of a possible association between continuous positive airway pressure (CPAP) devices and postoperative bleb-related infection. Observations: A 57-year old patient on CPAP presented with unilateral bleb-associated endophthalmitis 32 months after routine ExPress Trabeculectomy with mitomycin C. The offending organism, Streptococcus mitis, is a nonmotile and generally non-virulent pathogen which predominates in the normal human respiratory flora. Conclusions and importance: This conceptual report underscores a potential relationship between CPAP use and bleb-associated endophthalmitis. Streptococcal species are the most commonly reported causative organisms in bleb-associated endophthalmitis, and S. mitis is of particular concern as the most abundant microbe among all human oral flora. A logical risk factor for infection, the CPAP device may inadvertently deliver such organisms to the vulnerable conjunctival filtering bleb. Keywords: Endophthalmitis, Bleb, Mitomycin C, Express trabeculectomy, Continuous positive airway pressure, Streptococcus mitis |
| first_indexed | 2024-12-10T23:28:53Z |
| format | Article |
| id | doaj.art-6b40aeb73495437c8650fe4f099e8e0c |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-10T23:28:53Z |
| publishDate | 2018-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-6b40aeb73495437c8650fe4f099e8e0c2022-12-22T01:29:27ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362018-06-01108790Late-onset bleb-associated endophthalmitis and continuous positive airway pressureErich J. Berg0John B. Davies1Mark R. Buboltz2Thomas W. Samuelson3Clinical Research Department, Minnesota Eye Consultants, P.A. 9801 Dupont Avenue S. #200, Bloomington, MN 55431, USA; Corresponding author.VitreoRetinal Surgery, P.A. 710 East 24th Street #103, Minneapolis, MN 55404, USAClinical Research Department, Minnesota Eye Consultants, P.A. 9801 Dupont Avenue S. #200, Bloomington, MN 55431, USAClinical Research Department, Minnesota Eye Consultants, P.A. 9801 Dupont Avenue S. #200, Bloomington, MN 55431, USAPurpose: To raise awareness of a possible association between continuous positive airway pressure (CPAP) devices and postoperative bleb-related infection. Observations: A 57-year old patient on CPAP presented with unilateral bleb-associated endophthalmitis 32 months after routine ExPress Trabeculectomy with mitomycin C. The offending organism, Streptococcus mitis, is a nonmotile and generally non-virulent pathogen which predominates in the normal human respiratory flora. Conclusions and importance: This conceptual report underscores a potential relationship between CPAP use and bleb-associated endophthalmitis. Streptococcal species are the most commonly reported causative organisms in bleb-associated endophthalmitis, and S. mitis is of particular concern as the most abundant microbe among all human oral flora. A logical risk factor for infection, the CPAP device may inadvertently deliver such organisms to the vulnerable conjunctival filtering bleb. Keywords: Endophthalmitis, Bleb, Mitomycin C, Express trabeculectomy, Continuous positive airway pressure, Streptococcus mitishttp://www.sciencedirect.com/science/article/pii/S245199361730169X |
| spellingShingle | Erich J. Berg John B. Davies Mark R. Buboltz Thomas W. Samuelson Late-onset bleb-associated endophthalmitis and continuous positive airway pressure American Journal of Ophthalmology Case Reports |
| title | Late-onset bleb-associated endophthalmitis and continuous positive airway pressure |
| title_full | Late-onset bleb-associated endophthalmitis and continuous positive airway pressure |
| title_fullStr | Late-onset bleb-associated endophthalmitis and continuous positive airway pressure |
| title_full_unstemmed | Late-onset bleb-associated endophthalmitis and continuous positive airway pressure |
| title_short | Late-onset bleb-associated endophthalmitis and continuous positive airway pressure |
| title_sort | late onset bleb associated endophthalmitis and continuous positive airway pressure |
| url | http://www.sciencedirect.com/science/article/pii/S245199361730169X |
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