Phenylketonuria: central nervous system and microbiome interaction
Phenylketonuria (PKU) is an autosomal recessive inborn error of metabolism characterized by increased phenylalanine (Phe) levels causing an inadequate neurodevelopment; the treatment of PKU is a Phe-restricting diet, and as such it can modulate the intestinal microbiome of the individual, generating...
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| Format: | Article |
| Language: | English |
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Hygeia Press di Corridori Marinella
2017-06-01
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| Series: | Journal of Pediatric and Neonatal Individualized Medicine |
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| Online Access: | https://www.jpnim.com/index.php/jpnim/article/view/475 |
| _version_ | 1818970872834162688 |
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| author | Demian Arturo Herrera Morban |
| author_facet | Demian Arturo Herrera Morban |
| author_sort | Demian Arturo Herrera Morban |
| collection | DOAJ |
| description | Phenylketonuria (PKU) is an autosomal recessive inborn error of metabolism characterized by increased phenylalanine (Phe) levels causing an inadequate neurodevelopment; the treatment of PKU is a Phe-restricting diet, and as such it can modulate the intestinal microbiome of the individual, generating central nervous system secondary disturbances that, added to the baseline disturbance, can influence the outcome of the disease. |
| first_indexed | 2024-12-20T14:43:23Z |
| format | Article |
| id | doaj.art-6b41cbf4c84848f1a5135aba66f1712c |
| institution | Directory Open Access Journal |
| issn | 2281-0692 |
| language | English |
| last_indexed | 2024-12-20T14:43:23Z |
| publishDate | 2017-06-01 |
| publisher | Hygeia Press di Corridori Marinella |
| record_format | Article |
| series | Journal of Pediatric and Neonatal Individualized Medicine |
| spelling | doaj.art-6b41cbf4c84848f1a5135aba66f1712c2022-12-21T19:37:11ZengHygeia Press di Corridori MarinellaJournal of Pediatric and Neonatal Individualized Medicine2281-06922017-06-0162e060207e06020710.7363/060207401Phenylketonuria: central nervous system and microbiome interactionDemian Arturo Herrera Morban0Department of Pediatrics, Hospital Infantil Dr. Robert Reid Cabral and Universidad Iberoamericana (UNIBE), Santo Domingo, Dominican RepublicPhenylketonuria (PKU) is an autosomal recessive inborn error of metabolism characterized by increased phenylalanine (Phe) levels causing an inadequate neurodevelopment; the treatment of PKU is a Phe-restricting diet, and as such it can modulate the intestinal microbiome of the individual, generating central nervous system secondary disturbances that, added to the baseline disturbance, can influence the outcome of the disease.https://www.jpnim.com/index.php/jpnim/article/view/475phenylalaninephenylketonuriamicrobiomeglial cellsneurogenesis |
| spellingShingle | Demian Arturo Herrera Morban Phenylketonuria: central nervous system and microbiome interaction Journal of Pediatric and Neonatal Individualized Medicine phenylalanine phenylketonuria microbiome glial cells neurogenesis |
| title | Phenylketonuria: central nervous system and microbiome interaction |
| title_full | Phenylketonuria: central nervous system and microbiome interaction |
| title_fullStr | Phenylketonuria: central nervous system and microbiome interaction |
| title_full_unstemmed | Phenylketonuria: central nervous system and microbiome interaction |
| title_short | Phenylketonuria: central nervous system and microbiome interaction |
| title_sort | phenylketonuria central nervous system and microbiome interaction |
| topic | phenylalanine phenylketonuria microbiome glial cells neurogenesis |
| url | https://www.jpnim.com/index.php/jpnim/article/view/475 |
| work_keys_str_mv | AT demianarturoherreramorban phenylketonuriacentralnervoussystemandmicrobiomeinteraction |