Recent Advances of Fluorescence Probes for Imaging of Ferroptosis Process
Ferroptosis is an iron−dependent form of regulated cell death. It has attracted more and more research interests since it was found because of its potential physiological and pathological roles. In recent years, many efforts have been made for the developments and applications of selective fluoresce...
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| Format: | Article |
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MDPI AG
2022-06-01
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| Series: | Chemosensors |
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| Online Access: | https://www.mdpi.com/2227-9040/10/6/233 |
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| author | Hongyu Li Yan An Jie Gao Mingyan Yang Junjun Luo Xinmin Li Jiajia Lv Xiaohua Li Zeli Yuan Huimin Ma |
| author_facet | Hongyu Li Yan An Jie Gao Mingyan Yang Junjun Luo Xinmin Li Jiajia Lv Xiaohua Li Zeli Yuan Huimin Ma |
| author_sort | Hongyu Li |
| collection | DOAJ |
| description | Ferroptosis is an iron−dependent form of regulated cell death. It has attracted more and more research interests since it was found because of its potential physiological and pathological roles. In recent years, many efforts have been made for the developments and applications of selective fluorescence probes for real−time and in situ tracking of bioactive species during ferroptosis process, which is necessary and significant to further study the modulation mechanisms and pathological functions of ferroptosis. In this review, we will focus on summarizing the newly developed fluorescence probes that have been applied for ferroptosis imaging in the recent years, and comprehensively discussing their design strategies, including the probes for iron, reactive oxygen species, biothiols and intracellular microenvironmental factors. |
| first_indexed | 2024-03-10T00:08:08Z |
| format | Article |
| id | doaj.art-6b432be1833c466fae0d79c902bc61f7 |
| institution | Directory Open Access Journal |
| issn | 2227-9040 |
| language | English |
| last_indexed | 2024-03-10T00:08:08Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemosensors |
| spelling | doaj.art-6b432be1833c466fae0d79c902bc61f72023-11-23T16:04:23ZengMDPI AGChemosensors2227-90402022-06-0110623310.3390/chemosensors10060233Recent Advances of Fluorescence Probes for Imaging of Ferroptosis ProcessHongyu Li0Yan An1Jie Gao2Mingyan Yang3Junjun Luo4Xinmin Li5Jiajia Lv6Xiaohua Li7Zeli Yuan8Huimin Ma9College of Pharmacy, Zunyi Medical University, Zunyi 563003, ChinaCollege of Pharmacy, Zunyi Medical University, Zunyi 563003, ChinaCollege of Pharmacy, Zunyi Medical University, Zunyi 563003, ChinaCollege of Pharmacy, Zunyi Medical University, Zunyi 563003, ChinaCollege of Pharmacy, Zunyi Medical University, Zunyi 563003, ChinaCollege of Pharmacy, Zunyi Medical University, Zunyi 563003, ChinaCollege of Pharmacy, Zunyi Medical University, Zunyi 563003, ChinaKey Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, ChinaCollege of Pharmacy, Zunyi Medical University, Zunyi 563003, ChinaKey Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, ChinaFerroptosis is an iron−dependent form of regulated cell death. It has attracted more and more research interests since it was found because of its potential physiological and pathological roles. In recent years, many efforts have been made for the developments and applications of selective fluorescence probes for real−time and in situ tracking of bioactive species during ferroptosis process, which is necessary and significant to further study the modulation mechanisms and pathological functions of ferroptosis. In this review, we will focus on summarizing the newly developed fluorescence probes that have been applied for ferroptosis imaging in the recent years, and comprehensively discussing their design strategies, including the probes for iron, reactive oxygen species, biothiols and intracellular microenvironmental factors.https://www.mdpi.com/2227-9040/10/6/233ferroptosisfluorescence probeironreactive oxygen speciesbiothiolsintracellular microenvironment |
| spellingShingle | Hongyu Li Yan An Jie Gao Mingyan Yang Junjun Luo Xinmin Li Jiajia Lv Xiaohua Li Zeli Yuan Huimin Ma Recent Advances of Fluorescence Probes for Imaging of Ferroptosis Process Chemosensors ferroptosis fluorescence probe iron reactive oxygen species biothiols intracellular microenvironment |
| title | Recent Advances of Fluorescence Probes for Imaging of Ferroptosis Process |
| title_full | Recent Advances of Fluorescence Probes for Imaging of Ferroptosis Process |
| title_fullStr | Recent Advances of Fluorescence Probes for Imaging of Ferroptosis Process |
| title_full_unstemmed | Recent Advances of Fluorescence Probes for Imaging of Ferroptosis Process |
| title_short | Recent Advances of Fluorescence Probes for Imaging of Ferroptosis Process |
| title_sort | recent advances of fluorescence probes for imaging of ferroptosis process |
| topic | ferroptosis fluorescence probe iron reactive oxygen species biothiols intracellular microenvironment |
| url | https://www.mdpi.com/2227-9040/10/6/233 |
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