Small intestine morphology and recovery after drug-induced colitis in proglucagon-derived peptides knockout mice
Objective. Dipeptidyl peptidase (DPP)-4 inhibitors inactivate glucagon-like peptide (GLP)-1, GLP-2, and other hormones by degradation. Administration of a DPP-4 inhibitor or GLP-2 analog stimulates intestinal growth and facilitates the restoration of mucosal damage caused by drug-induced colitis in...
Main Authors: | Masanobu Matsushita, Osamu Watanabe, Takafumi Ando, Osamu Maeda, Ryoji Miyahara, Masanao Nakamura, Takeshi Yamamura, Hidemi Goto, Yoshiki Hirooka |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2016-12-01
|
Series: | Cogent Medicine |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/2331205X.2016.1215783 |
Similar Items
-
<i>Roseburia intestinalis</i> Modulates PYY Expression in a New a Multicellular Model including Enteroendocrine Cells
by: Thomas Gautier, et al.
Published: (2022-11-01) -
Integrative analysis revealed the role of glucagon-like peptide-2 in improving experimental colitis in mice by inhibiting inflammatory pathways, regulating glucose metabolism, and modulating gut microbiota
by: Dongyue Li, et al.
Published: (2023-05-01) -
Blockade of glucagon increases muscle mass and alters fiber type composition in mice deficient in proglucagon‐derived peptides
by: Shinji Ueno, et al.
Published: (2023-09-01) -
The associations of incretin hormone concentration with gestational diabetes mellitus
by: Tatiana V. Saprina, et al.
Published: (2016-05-01) -
BI 456906: Discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy
by: Tina Zimmermann, et al.
Published: (2022-12-01)