Design of Nanostructured Hybrid Electrodes Based on a Liquid Crystalline Zn(II) Coordination Complex-Carbon Nanotubes Composition for the Specific Electrochemical Sensing of Uric Acid
A metallomesogen based on an Zn(II) coordination complex was employed as precursor to obtain a complex matrix nanoplatform for the fabrication of a high-performance electrochemical hybrid sensor. Three representative paste electrodes, which differ by the weight ratio between Zn(II) metallomesogen an...
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MDPI AG
2022-11-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/23/4215 |
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| author | Sorina Negrea Adelina A. Andelescu Sorina Ilies (b. Motoc) Carmen Cretu Liliana Cseh Mircea Rastei Bertrand Donnio Elisabeta I. Szerb Florica Manea |
| author_facet | Sorina Negrea Adelina A. Andelescu Sorina Ilies (b. Motoc) Carmen Cretu Liliana Cseh Mircea Rastei Bertrand Donnio Elisabeta I. Szerb Florica Manea |
| author_sort | Sorina Negrea |
| collection | DOAJ |
| description | A metallomesogen based on an Zn(II) coordination complex was employed as precursor to obtain a complex matrix nanoplatform for the fabrication of a high-performance electrochemical hybrid sensor. Three representative paste electrodes, which differ by the weight ratio between Zn(II) metallomesogen and carbon nanotubes (CNT), i.e., PE_01, PE_02 and PE_03, were obtained by mixing the materials in different amounts. The composition with the largest amount of CNT with respect to Zn complex, i.e., PE_03, gives the best electrochemical signal for uric acid detection by cyclic voltammetry in an alkaline medium. The amphiphilic structure of the Zn(II) coordination complex likely induces a regular separation between the metal centers favoring the redox system through their reduction, followed by stripping, and is characterized by enhanced electrocatalytic activity towards uric acid oxidation. The comparative detection of uric acid between the PE_03 paste electrode and the commercial zinc electrode demonstrated the superiority of the former, and its great potential for the development of advanced electrochemical detection of uric acid. Advanced electrochemical techniques, such as differential-pulsed voltammetry (DPV) and square-wave voltammetry (SWV), allowed for the highly sensitive detection of uric acid in aqueous alkaline solutions. In addition, a good and fast amperometric signal for uric acid detection was achieved by multiple-pulsed amperometry, which was validated by urine analysis. |
| first_indexed | 2024-03-09T17:38:42Z |
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| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T17:38:42Z |
| publishDate | 2022-11-01 |
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| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-6b461c6a8ea344a3ba3e5438be11dd2c2023-11-24T11:47:22ZengMDPI AGNanomaterials2079-49912022-11-011223421510.3390/nano12234215Design of Nanostructured Hybrid Electrodes Based on a Liquid Crystalline Zn(II) Coordination Complex-Carbon Nanotubes Composition for the Specific Electrochemical Sensing of Uric AcidSorina Negrea0Adelina A. Andelescu1Sorina Ilies (b. Motoc)2Carmen Cretu3Liliana Cseh4Mircea Rastei5Bertrand Donnio6Elisabeta I. Szerb7Florica Manea8Department of Applied Chemistry and Engineering of Inorganic Compounds and Environment, Politehnica University of Timisoara, Bvd. Vasile Parvan No. 6, 300223 Timisoara, Romania“Coriolan Drăgulescu” Institute of Chemistry, Romanian Academy, 24 Mihai Viteazu Bvd., 300223 Timisoara, Romania“Coriolan Drăgulescu” Institute of Chemistry, Romanian Academy, 24 Mihai Viteazu Bvd., 300223 Timisoara, Romania“Coriolan Drăgulescu” Institute of Chemistry, Romanian Academy, 24 Mihai Viteazu Bvd., 300223 Timisoara, Romania“Coriolan Drăgulescu” Institute of Chemistry, Romanian Academy, 24 Mihai Viteazu Bvd., 300223 Timisoara, RomaniaInstitut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), CNRS-Université de Strasbourg (UMR7504), 67034 Strasbourg, FranceInstitut de Physique et Chimie des Matériaux de Strasbourg (IPCMS), CNRS-Université de Strasbourg (UMR7504), 67034 Strasbourg, France“Coriolan Drăgulescu” Institute of Chemistry, Romanian Academy, 24 Mihai Viteazu Bvd., 300223 Timisoara, RomaniaDepartment of Applied Chemistry and Engineering of Inorganic Compounds and Environment, Politehnica University of Timisoara, Bvd. Vasile Parvan No. 6, 300223 Timisoara, RomaniaA metallomesogen based on an Zn(II) coordination complex was employed as precursor to obtain a complex matrix nanoplatform for the fabrication of a high-performance electrochemical hybrid sensor. Three representative paste electrodes, which differ by the weight ratio between Zn(II) metallomesogen and carbon nanotubes (CNT), i.e., PE_01, PE_02 and PE_03, were obtained by mixing the materials in different amounts. The composition with the largest amount of CNT with respect to Zn complex, i.e., PE_03, gives the best electrochemical signal for uric acid detection by cyclic voltammetry in an alkaline medium. The amphiphilic structure of the Zn(II) coordination complex likely induces a regular separation between the metal centers favoring the redox system through their reduction, followed by stripping, and is characterized by enhanced electrocatalytic activity towards uric acid oxidation. The comparative detection of uric acid between the PE_03 paste electrode and the commercial zinc electrode demonstrated the superiority of the former, and its great potential for the development of advanced electrochemical detection of uric acid. Advanced electrochemical techniques, such as differential-pulsed voltammetry (DPV) and square-wave voltammetry (SWV), allowed for the highly sensitive detection of uric acid in aqueous alkaline solutions. In addition, a good and fast amperometric signal for uric acid detection was achieved by multiple-pulsed amperometry, which was validated by urine analysis.https://www.mdpi.com/2079-4991/12/23/4215Zn(II)metallomesogennanocomposite paste electrodecarbon nanotubessensoruric acid |
| spellingShingle | Sorina Negrea Adelina A. Andelescu Sorina Ilies (b. Motoc) Carmen Cretu Liliana Cseh Mircea Rastei Bertrand Donnio Elisabeta I. Szerb Florica Manea Design of Nanostructured Hybrid Electrodes Based on a Liquid Crystalline Zn(II) Coordination Complex-Carbon Nanotubes Composition for the Specific Electrochemical Sensing of Uric Acid Nanomaterials Zn(II) metallomesogen nanocomposite paste electrode carbon nanotubes sensor uric acid |
| title | Design of Nanostructured Hybrid Electrodes Based on a Liquid Crystalline Zn(II) Coordination Complex-Carbon Nanotubes Composition for the Specific Electrochemical Sensing of Uric Acid |
| title_full | Design of Nanostructured Hybrid Electrodes Based on a Liquid Crystalline Zn(II) Coordination Complex-Carbon Nanotubes Composition for the Specific Electrochemical Sensing of Uric Acid |
| title_fullStr | Design of Nanostructured Hybrid Electrodes Based on a Liquid Crystalline Zn(II) Coordination Complex-Carbon Nanotubes Composition for the Specific Electrochemical Sensing of Uric Acid |
| title_full_unstemmed | Design of Nanostructured Hybrid Electrodes Based on a Liquid Crystalline Zn(II) Coordination Complex-Carbon Nanotubes Composition for the Specific Electrochemical Sensing of Uric Acid |
| title_short | Design of Nanostructured Hybrid Electrodes Based on a Liquid Crystalline Zn(II) Coordination Complex-Carbon Nanotubes Composition for the Specific Electrochemical Sensing of Uric Acid |
| title_sort | design of nanostructured hybrid electrodes based on a liquid crystalline zn ii coordination complex carbon nanotubes composition for the specific electrochemical sensing of uric acid |
| topic | Zn(II) metallomesogen nanocomposite paste electrode carbon nanotubes sensor uric acid |
| url | https://www.mdpi.com/2079-4991/12/23/4215 |
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