Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation
Heme oxygenase catalyzes the rate-limiting step in heme degradation in order to generate biliverdin, carbon monoxide (CO), and iron. The inducible form of the enzyme, heme oxygenase-1 (HO-1), exerts a central role in cellular protection. The substrate, heme, is a potent pro-oxidant that can accelera...
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| Format: | Artikel |
| Sprache: | English |
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MDPI AG
2021-02-01
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| Schriftenreihe: | Cells |
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| Online Zugang: | https://www.mdpi.com/2073-4409/10/3/515 |